Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity

doi:10.1016/j.cej.2017.08.026

NWIPB OpenIR

	Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity
	Huang, Lunjie 1; Zhang, Wentao 1; Chen, Kai 1; Zhu, Wenxin 1; Liu, Xinnan 1; Wang, Rong 1; Zhang, Xu 1; Hu, Na2 ; Suo, Yourui2 ; Wang, Jianlong 1
	2017-12-15
发表期刊	CHEMICAL ENGINEERING JOURNAL
ISSN	1385-8947
卷号	330 页码:746-752
文章类型	Article
摘要	Nanozymes, as a robust alternative to natural enzyme, usually suffer from unsatisfactory catalytic efficiency and limited modulating flexibility. Herein, we proposed a novel strategy to conquer these disadvantages relying on the facet-selective response of external trigger molecule which boosts the oxidase-like catalysis of nanoceria. Results indicate that the trigger molecule (i.e., sulfate ion) prefers to bind to the rod-like nanoceria (on its unique {1 1 0} facets) rather than nanopolyhedra or nanocubes. Sulfate ion-treated CeO2 nanorods (SO42- /CeO2 NRs) became modulatable oxidase mimetics of high efficiency, and the catalytic efficiency (k(cat)/K-m) of SO42- /CeO2 NRs improved by nearly 20-fold (versus that of the naked CeO2 NRs) for 3,3 ',5,5 '-tetramethylbenzidine (TMB) oxidation. This modulating strategy, together with the mechanism behind, is finally applied to develop colorimetric biosensors, which paves the way for embedding the system in biological and environmental networks.
关键词	Biocatalysis Colorimetric Biosensor Facet Dependence Modulating Strategy Nanoceria Oxidase Mimics
WOS标题词	Science & Technology ; Technology
DOI	10.1016/j.cej.2017.08.026
关键词[WOS]	PEROXIDASE-LIKE ACTIVITY ; STRUCTURE DEPENDENCE ; CERIA NANOPARTICLES ; ARTIFICIAL ENZYMES ; CATALYTIC-ACTIVITY ; MIMETIC ACTIVITY ; NANOSCALE CERIA ; NANOCERIA ; NANOCRYSTALS ; NANOZYMES
收录类别	SCI
语种	英语
项目资助者	National Natural Science Foundation of China(21675127) ; Fundamental Research Funds for the Northwest A&F University of China(2014YB093 ; 2452015257)
WOS研究方向	Engineering
WOS类目	Engineering, Environmental ; Engineering, Chemical
WOS记录号	WOS:000414083300071
出版者	ELSEVIER SCIENCE SA
引用统计	被引频次：68[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/10368
专题	中国科学院西北高原生物研究所
通讯作者	Wang, Jianlong
作者单位	1.Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining 810008, Qinghai, Peoples R China
推荐引用方式 GB/T 7714	Huang, Lunjie,Zhang, Wentao,Chen, Kai,et al. Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity[J]. CHEMICAL ENGINEERING JOURNAL,2017,330:746-752.
APA	Huang, Lunjie.,Zhang, Wentao.,Chen, Kai.,Zhu, Wenxin.,Liu, Xinnan.,...&Wang, Jianlong.(2017).Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity.CHEMICAL ENGINEERING JOURNAL,330,746-752.
MLA	Huang, Lunjie,et al."Facet-selective response of trigger molecule to CeO2 {110} for up-regulating oxidase-like activity".CHEMICAL ENGINEERING JOURNAL 330(2017):746-752.