NWIPB OpenIR
Photoinduced electron transfer from polymer-templated Ag nanoclusters to G-quadruplex-hemin complexes for the construction of versatile biosensors and logic gate applications
Qu, Fei1,2; Mao, Beibei1,2,3; Xue, Fangfang1,2; Xia, Lian1,2; You, Jinmao1,2,4; Song, Cuihua1,2
2018-03-01
Source PublicationANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume410Issue:8Pages:2211-2219
SubtypeArticle
AbstractIn this paper, fluorescent Ag nanoclusters (Ag NCs) templated by hyperbranched polyethyleneimine (PEI) are utilized as a versatile probe through the photoinduced electron transfer (PET) between PEI-Ag NCs and G-quadruplex-hemin complexes. In the presence of hemin and target molecule, the specific conjugation with its aptamer induces the conformational change of the DNA sequence, releasing the G-quadruplex sequence part. Once the G-quadruplex-hemin complexes are introduced, electron transfer from the PEI-Ag NCs to G-quadruplex-hemin complexes occurs, resulting in fluorescence quenching. Through changing the sensing DNA sequence, this novel PET system enables the specific detection of target DNA and adenosine triphosphate (ATP) with the wide linear range of 1-200 nM and 5-500 nM, respectively, and the corresponding limit of detection as low as 0.3 nM for target DNA and 1.5 nM for ATP. In addition, the proposed method is successfully applied to the determination of ATP in human serum samples with satisfactory recoveries, and a logic gate is fabricated using target molecules and hemin as inputs and the fluorescence signal of PEI-Ag NCs as an output.
KeywordAg Nanoclusters G-quadruplex-hemin Complexes Adenosine Triphosphate Target Dna Logic Gate
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine ; Physical Sciences
DOI10.1007/s00216-018-0887-z
WOS KeywordLABEL-FREE APTASENSOR ; ZNS QUANTUM DOTS ; SILVER NANOCLUSTERS ; SENSITIVE DETECTION ; SERUM-ALBUMIN ; FLUORESCENCE ; ATP ; PROBES ; SENSOR
Indexed BySCI
Language英语
Funding OrganizationNational Natural Science Foundation of China (Youth Fund Project)(21405093) ; Natural Science Foundation of Shandong Province(ZR2015CM040) ; Scientific Research Foundation of Qufu Normal University(BSQD20130117)
WOS Research AreaBiochemistry & Molecular Biology ; Chemistry
WOS SubjectBiochemical Research Methods ; Chemistry, Analytical
WOS IDWOS:000426466800015
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://210.75.249.4/handle/363003/13328
Collection中国科学院西北高原生物研究所
Affiliation1.Qufu Normal Univ, Key Lab Life Organ Anal, Qufu 273165, Shandong, Peoples R China
2.Qufu Normal Univ, Key Lab Pharmaceut Intermediates & Anal Nat Med, Qufu 273165, Shandong, Peoples R China
3.Juye Cty Vocat Secondary Sch, Heze 274000, Shandong, Peoples R China
4.Chinese Acad Sci, Northwest Inst Plateau Biol, Xining 810001, Qinghai, Peoples R China
Recommended Citation
GB/T 7714
Qu, Fei,Mao, Beibei,Xue, Fangfang,et al. Photoinduced electron transfer from polymer-templated Ag nanoclusters to G-quadruplex-hemin complexes for the construction of versatile biosensors and logic gate applications[J]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2018,410(8):2211-2219.
APA Qu, Fei,Mao, Beibei,Xue, Fangfang,Xia, Lian,You, Jinmao,&Song, Cuihua.(2018).Photoinduced electron transfer from polymer-templated Ag nanoclusters to G-quadruplex-hemin complexes for the construction of versatile biosensors and logic gate applications.ANALYTICAL AND BIOANALYTICAL CHEMISTRY,410(8),2211-2219.
MLA Qu, Fei,et al."Photoinduced electron transfer from polymer-templated Ag nanoclusters to G-quadruplex-hemin complexes for the construction of versatile biosensors and logic gate applications".ANALYTICAL AND BIOANALYTICAL CHEMISTRY 410.8(2018):2211-2219.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Qu, Fei]'s Articles
[Mao, Beibei]'s Articles
[Xue, Fangfang]'s Articles
Baidu academic
Similar articles in Baidu academic
[Qu, Fei]'s Articles
[Mao, Beibei]'s Articles
[Xue, Fangfang]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Qu, Fei]'s Articles
[Mao, Beibei]'s Articles
[Xue, Fangfang]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.