Knowledge Management System of Northwest Institute of Plateau Biology, CAS
Highly sensitive and selective colorimetric detection of glutathione via enhanced Fenton-like reaction of magnetic metal organic framework | |
Zhang, Ying1; Zhang, Wentao1; Chen, Kai1; Yang, Qingfeng1; Hu, Na2; Suo, Yourui2; Wang, Jianlong1 | |
2018-06-01 | |
发表期刊 | SENSORS AND ACTUATORS B-CHEMICAL |
卷号 | 262页码:95-101 |
文章类型 | Article |
摘要 | Glutathione (GSH) as a biothiol is an essential endogenous antioxidant related to various diseases. Since all the biothiols possess similar structures and reaction activities, it is still challenging to detect GSH over cysteine (Cys) and homocysteine (Hcy). In this contribution, we propose a novel approach to sensitively and selectively detect GSH based on Fe3O4/MIL-88-H2O2-methylene blue (MB) heterogeneous system via enhanced Fenton-like reaction. The magnetic metal organic framework (Fe3O4/MIL-88) exhibits synergistic effect on Fenton-like reaction by combining Fe3O4 with MIL-88. In this system, GSH can facilitate the degradation of MB in the presence of Fe3O4/MIL-88 and H2O2, so a detection method for GSH is established via a turn-off colorimetric process. Under the optimal conditions, this approach presents a good linear response to GSH concentration in the ranges of 0-0.55 mu M and 0.55-3 mu M, with a detection limit of 36.9 nM (3 delta/S). Furthermore, the excellent sensitive and selective responses to GSH in serum sample make this assay a promising tool for biological applications due to its simplicity, high efficiency and low cost. (C) 2018 Elsevier B.V. All rights reserved. |
关键词 | Fe3o4/mil-88 Composite Methylene Blue Dye Enhanced Fenton-like Catalysis Glutathione Detection Colorimetric Biosensor |
WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
DOI | 10.1016/j.snb.2018.01.221 |
关键词[WOS] | METHYLENE-BLUE ; PEROXIDASE MIMICS ; NANOPARTICLES ; GLUCOSE ; HOMOCYSTEINE ; NANOSHEETS ; SURFACE ; ENZYME ; SERUM ; FLUORESCENCE |
收录类别 | SCI |
语种 | 英语 |
项目资助者 | National Natural Science Foundation of China(21675127) ; Fundamental Research Funds for the Northwest A&F University of China(2014YB093 ; 2452015257) |
WOS研究方向 | Chemistry ; Electrochemistry ; Instruments & Instrumentation |
WOS类目 | Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation |
WOS记录号 | WOS:000427460600013 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/13355 |
专题 | 中国科学院西北高原生物研究所 |
作者单位 | 1.Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining 810008, Qinghai, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Ying,Zhang, Wentao,Chen, Kai,et al. Highly sensitive and selective colorimetric detection of glutathione via enhanced Fenton-like reaction of magnetic metal organic framework[J]. SENSORS AND ACTUATORS B-CHEMICAL,2018,262:95-101. |
APA | Zhang, Ying.,Zhang, Wentao.,Chen, Kai.,Yang, Qingfeng.,Hu, Na.,...&Wang, Jianlong.(2018).Highly sensitive and selective colorimetric detection of glutathione via enhanced Fenton-like reaction of magnetic metal organic framework.SENSORS AND ACTUATORS B-CHEMICAL,262,95-101. |
MLA | Zhang, Ying,et al."Highly sensitive and selective colorimetric detection of glutathione via enhanced Fenton-like reaction of magnetic metal organic framework".SENSORS AND ACTUATORS B-CHEMICAL 262(2018):95-101. |
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