Effects of hypoxia on contents of essential elements in pika and rat heart

NWIPB OpenIR

	Effects of hypoxia on contents of essential elements in pika and rat heart
	Suo, YR ; Wang, HQ ; Zhang, BC
	2005-02-01
发表期刊	BIOLOGICAL TRACE ELEMENT RESEARCH
卷号	103 期号:2 页码:147-153
文章类型	Article
摘要	The effects of hypoxia on the levels of essential macroelements and trace elements (K, Na, Ca, Mg, Cu, Zn, Fe, and Mn) in the heart muscles of Wistar rats and plateau pikas (Ochotona curzoniae) were studied by atomic absorption spectrometry. Unlike the rat, the plateau pika is tolerant to hypoxia. The levels of K, Na, and the trace element Mn were not significantly changed in rat or pika hearts after exposure to hypoxia for 1, 10, or 25 d at simulated altitudes of 5000 and 7000 m. Other minerals (Ca, Mg, Cu, Zn, and Fe) were significantly affected by hypoxia and the levels followed different time-courses under different hypoxic regimes in these two animals. There were marked differences between the rat and pika in myocardial accumulation of essential elements such as Ca, which was increased to high levels in the rat but not affected in the pika. The results suggest that hypoxia affects animal physiological mechanisms by regulating the levels of essential elements.; The effects of hypoxia on the levels of essential macroelements and trace elements (K, Na, Ca, Mg, Cu, Zn, Fe, and Mn) in the heart muscles of Wistar rats and plateau pikas (Ochotona curzoniae) were studied by atomic absorption spectrometry. Unlike the rat, the plateau pika is tolerant to hypoxia. The levels of K, Na, and the trace element Mn were not significantly changed in rat or pika hearts after exposure to hypoxia for 1, 10, or 25 d at simulated altitudes of 5000 and 7000 m. Other minerals (Ca, Mg, Cu, Zn, and Fe) were significantly affected by hypoxia and the levels followed different time-courses under different hypoxic regimes in these two animals. There were marked differences between the rat and pika in myocardial accumulation of essential elements such as Ca, which was increased to high levels in the rat but not affected in the pika. The results suggest that hypoxia affects animal physiological mechanisms by regulating the levels of essential elements.
关键词	Hypoxia Pika Rat Myocardium Essential Elements
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
学科领域	生物化学
关键词[WOS]	PHYSICAL-ACTIVITY ; ISCHEMIA
收录类别	SCI
语种	英语
WOS研究方向	Biochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS类目	Biochemistry & Molecular Biology ; Endocrinology & Metabolism
WOS记录号	WOS:000228961300005
引用统计	被引频次：6[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/1372
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, NW Plateau Inst Biol, Xining 710001, Peoples R China
推荐引用方式 GB/T 7714	Suo, YR,Wang, HQ,Zhang, BC. Effects of hypoxia on contents of essential elements in pika and rat heart[J]. BIOLOGICAL TRACE ELEMENT RESEARCH,2005,103(2):147-153.
APA	Suo, YR,Wang, HQ,&Zhang, BC.(2005).Effects of hypoxia on contents of essential elements in pika and rat heart.BIOLOGICAL TRACE ELEMENT RESEARCH,103(2),147-153.
MLA	Suo, YR,et al."Effects of hypoxia on contents of essential elements in pika and rat heart".BIOLOGICAL TRACE ELEMENT RESEARCH 103.2(2005):147-153.