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Antioxidant xanthones from Swertia mussotii, a high altitude plant | |
Luo, Cui-Ting ; Mao, Shuang-Shuang ; Liu, Fang-Lan ; Yang, Mao-xun ; Chen, Heru ; Kurihara, Hiroshi ; Li, Yulin ; Chen, HR (reprint author), Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Huangpu Ave West 601, Guangzhou 510632, Guangdong, Peoples R China. | |
2013-12-01 | |
发表期刊 | FITOTERAPIA ; Luo, CT; Mao, SS; Liu, FL; Yang, MX; Chen, HR; Kurihara, H; Li, YL.Antioxidant xanthones from Swertia mussotii, a high altitude plant,FITOTERAPIA,2013,91():140-147 |
摘要 | Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-beta-D-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(beta-D-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(beta-D-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(beta-D-glucoside) (4), together with twenty-one known xanthones (5-25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORAC(FL) assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where I is the most active compound and 13 is the least one. A preliminary structure-activity relationship is also discussed. (C) 2013 Elsevier B.V. All rights reserved.; Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-beta-D-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(beta-D-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(beta-D-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(beta-D-glucoside) (4), together with twenty-one known xanthones (5-25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORAC(FL) assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where I is the most active compound and 13 is the least one. A preliminary structure-activity relationship is also discussed. (C) 2013 Elsevier B.V. All rights reserved. |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/16667 |
专题 | 中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Luo, Cui-Ting,Mao, Shuang-Shuang,Liu, Fang-Lan,et al. Antioxidant xanthones from Swertia mussotii, a high altitude plant[J]. FITOTERAPIA, Luo, CT; Mao, SS; Liu, FL; Yang, MX; Chen, HR; Kurihara, H; Li, YL.Antioxidant xanthones from Swertia mussotii, a high altitude plant,FITOTERAPIA,2013,91():140-147,2013. |
APA | Luo, Cui-Ting.,Mao, Shuang-Shuang.,Liu, Fang-Lan.,Yang, Mao-xun.,Chen, Heru.,...&Chen, HR .(2013).Antioxidant xanthones from Swertia mussotii, a high altitude plant.FITOTERAPIA. |
MLA | Luo, Cui-Ting,et al."Antioxidant xanthones from Swertia mussotii, a high altitude plant".FITOTERAPIA (2013). |
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