Chemical Species, Micromorphology, and XRD Fingerprint Analysis of Tibetan Medicine Zuotai Containing Mercury

NWIPB OpenIR

	Chemical Species, Micromorphology, and XRD Fingerprint Analysis of Tibetan Medicine Zuotai Containing Mercury
	Li, Cen ; Yang, Hongxia ; Du, Yuzhi ; Xiao, Yuancan ; Zhandui ; Sanglao ; Wang, Zhang ; Ladan, Duojie ; Bi, Hongtao ; Wei, Lixin
	2016
发表期刊	BIOINORGANIC CHEMISTRY AND APPLICATIONS
摘要	Zuotai (gTso thal) is one of the famous drugs containing mercury in Tibetan medicine. However, little is known about the chemical substance basis of its pharmacodynamics and the intrinsic link of different samples sources so far. Given this, energy dispersive spectrometry of X-ray (EDX), scanning electron microscopy (SEM), atomic force microscopy (AFM), and powder X-ray diffraction (XRD) were used to assay the elements, micromorphology, and phase composition of nine Zuotai samples from different regions, respectively; the XRD fingerprint features of Zuotai were analyzed by multivariate statistical analysis. EDX result shows that Zuotai contains Hg, S, O, Fe, Al, Cu, and other elements. SEM and AFM observations suggest that Zuotai is a kind of ancient nanodrug. Its particles are mainly in the range of 100-800 nm, which commonly further aggregate into 1-30 mu m loosely amorphous particles. XRD test shows that beta-HgS, S-8, and alpha-HgS are its main phase compositions. XRD fingerprint analysis indicates that the similarity degrees of nine samples are very high, and the results of multivariate statistical analysis are broadly consistent with sample sources. The present research has revealed the physicochemical characteristics of Zuotai, and it would play a positive role in interpreting this mysterious Tibetan drug.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/17567
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Li, Cen,Yang, Hongxia,Du, Yuzhi,et al. Chemical Species, Micromorphology, and XRD Fingerprint Analysis of Tibetan Medicine Zuotai Containing Mercury[J]. BIOINORGANIC CHEMISTRY AND APPLICATIONS,2016.
APA	Li, Cen.,Yang, Hongxia.,Du, Yuzhi.,Xiao, Yuancan.,Zhandui.,...&Wei, Lixin.(2016).Chemical Species, Micromorphology, and XRD Fingerprint Analysis of Tibetan Medicine Zuotai Containing Mercury.BIOINORGANIC CHEMISTRY AND APPLICATIONS.
MLA	Li, Cen,et al."Chemical Species, Micromorphology, and XRD Fingerprint Analysis of Tibetan Medicine Zuotai Containing Mercury".BIOINORGANIC CHEMISTRY AND APPLICATIONS (2016).