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Chemical constituents investigation of Daphne tangutica
Pan, Li1,2; Zhang, Xiao Feng2; Deng, Ye3; Zhou, Yan1; Wang, Huan2; Ding, Li Sheng1
2010
Source PublicationFITOTERAPIA
ISSN0367-326X
Volume81Issue:1Pages:38-41
SubtypeArticle
AbstractA phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Two compounds out of these isolates are new daphne diterpene analogs, and their structures were established as 1,2 alpha-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy- resiniferomol-14-benzonate, and 1,2 beta-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, respectively, on the basis of spectroscopic methods. Additionally, this is the first time that 13 known compounds have been isolated and identified from this traditional Tibetan medicinal plant. (C) 2009 Published by Elsevier B.V.; A phytochemical study of an ethanol-soluble extract from the root barks of Daphne tangutica Maxim., a traditional Tibetan herb medicine, led to the isolation of 30 compounds, including eight daphnane diterpenes, nine coumarines, six lignans, five phenylpropanoid derivatives, beta-sitosterol and p-hydroxy benzonate. Two compounds out of these isolates are new daphne diterpene analogs, and their structures were established as 1,2 alpha-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy- resiniferomol-14-benzonate, and 1,2 beta-dihydro-5 beta-hydroxy-6 alpha,7 alpha-epoxy-resiniferonol-14-benzonate, respectively, on the basis of spectroscopic methods. Additionally, this is the first time that 13 known compounds have been isolated and identified from this traditional Tibetan medicinal plant. (C) 2009 Published by Elsevier B.V.
KeywordDaphne Tangutica Thymelaeaceae Daphnane Diterpene Lignan Coumarine Phenylpropanoid Derivative
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordDITERPENES ; GLYCOSIDES
Indexed BySCI
Language英语
WOS Research AreaPharmacology & Pharmacy
WOS SubjectChemistry, Medicinal ; Pharmacology & Pharmacy
WOS IDWOS:000273967500008
Citation statistics
Cited Times:18[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://210.75.249.4/handle/363003/1758
Collection中国科学院西北高原生物研究所
Affiliation1.Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China
2.Chinese Acad Sci, NW Plateau Inst Biol, Xining 810001, Peoples R China
3.Ohio State Univ, Coll Pharm, Div Med Chem & Pharmacognosy, Columbus, OH 43210 USA
Recommended Citation
GB/T 7714
Pan, Li,Zhang, Xiao Feng,Deng, Ye,et al. Chemical constituents investigation of Daphne tangutica[J]. FITOTERAPIA,2010,81(1):38-41.
APA Pan, Li,Zhang, Xiao Feng,Deng, Ye,Zhou, Yan,Wang, Huan,&Ding, Li Sheng.(2010).Chemical constituents investigation of Daphne tangutica.FITOTERAPIA,81(1),38-41.
MLA Pan, Li,et al."Chemical constituents investigation of Daphne tangutica".FITOTERAPIA 81.1(2010):38-41.
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