Concentrations of the Active Constituents of the Tibetan Folk Medicine Qinjiao (Gentiana sect. Cruciata) within and between Taxonomic Species across the Qinghai-Tibetan Plateau

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	Concentrations of the Active Constituents of the Tibetan Folk Medicine Qinjiao (Gentiana sect. Cruciata) within and between Taxonomic Species across the Qinghai-Tibetan Plateau
	Zhou, Dangwei 1; Hou, Qinzheng 1,2; Si, Qinwen 1,2; Liu, Jianquan 3; Yang, Huiling 1
	2010
发表期刊	CHEMISTRY & BIODIVERSITY
ISSN	1612-1872
卷号	7 期号:8 页码:2088-2094
文章类型	Article
摘要	The Tibetan folk medicine Qinjiao is traditionally used to treat various conditions, and as main active constituents comprise four untold glycosides. i e loganic acid, swertiamarin, gentiopicroside, and sweroside The traditional crude medicine Qinjiao is derived from the dried roots of three species belonging to Gentiana sect Cruciata (Gentianaceae) growing in the Qinghai-Tibetan Plateau (QTP) In this study, we determined by HPLC the contents of the four main active constituents in the dried roots collected from 83 localities at different altitudes across the QTP The material was classified under the seven taxonomic species G straminea. C daliurica. C crassicaulis, C waltonii. G G ihassica, and G macrophylla Our results suggested that the four constituents were present in the roots of all seven species for all localities. but their concentrations varied greatly within and between species The level of gentiopicroside revealed to be the most dominant for all examined localities (2 1-12 4 mg/g). and G macrophylla PALL contained the highest concentration of all the four constituents at the species level Except for loganic acid in G officinalis, there was no significant correlation between the contents of these constituents and the altitude of the sampling localities These results suggest that all species of all origins can be used as reliable resource for the crude medicine Qinjiao However, a few species contain higher concentrations of the main active constituents. irrespective of their origin; The Tibetan folk medicine Qinjiao is traditionally used to treat various conditions, and as main active constituents comprise four untold glycosides. i e loganic acid, swertiamarin, gentiopicroside, and sweroside The traditional crude medicine Qinjiao is derived from the dried roots of three species belonging to Gentiana sect Cruciata (Gentianaceae) growing in the Qinghai-Tibetan Plateau (QTP) In this study, we determined by HPLC the contents of the four main active constituents in the dried roots collected from 83 localities at different altitudes across the QTP The material was classified under the seven taxonomic species G straminea. C daliurica. C crassicaulis, C waltonii. G G ihassica, and G macrophylla Our results suggested that the four constituents were present in the roots of all seven species for all localities. but their concentrations varied greatly within and between species The level of gentiopicroside revealed to be the most dominant for all examined localities (2 1-12 4 mg/g). and G macrophylla PALL contained the highest concentration of all the four constituents at the species level Except for loganic acid in G officinalis, there was no significant correlation between the contents of these constituents and the altitude of the sampling localities These results suggest that all species of all origins can be used as reliable resource for the crude medicine Qinjiao However, a few species contain higher concentrations of the main active constituents. irrespective of their origin
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
收录类别	SCI
语种	英语
WOS研究方向	Biochemistry & Molecular Biology ; Chemistry
WOS类目	Biochemistry & Molecular Biology ; Chemistry, Multidisciplinary
WOS记录号	WOS:000281489400020
引用统计	被引频次：17[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/1762
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Key Lab Adaptat & Evolut Plateau Biota, NW Plateau Inst Biol, Xining 810008, Qinghai, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Lanzhou Univ, Key Lab Arid & Grassland Ecol, Lanzhou 730000, Gansu, Peoples R China
推荐引用方式 GB/T 7714	Zhou, Dangwei,Hou, Qinzheng,Si, Qinwen,et al. Concentrations of the Active Constituents of the Tibetan Folk Medicine Qinjiao (Gentiana sect. Cruciata) within and between Taxonomic Species across the Qinghai-Tibetan Plateau[J]. CHEMISTRY & BIODIVERSITY,2010,7(8):2088-2094.
APA	Zhou, Dangwei,Hou, Qinzheng,Si, Qinwen,Liu, Jianquan,&Yang, Huiling.(2010).Concentrations of the Active Constituents of the Tibetan Folk Medicine Qinjiao (Gentiana sect. Cruciata) within and between Taxonomic Species across the Qinghai-Tibetan Plateau.CHEMISTRY & BIODIVERSITY,7(8),2088-2094.
MLA	Zhou, Dangwei,et al."Concentrations of the Active Constituents of the Tibetan Folk Medicine Qinjiao (Gentiana sect. Cruciata) within and between Taxonomic Species across the Qinghai-Tibetan Plateau".CHEMISTRY & BIODIVERSITY 7.8(2010):2088-2094.