NWIPB OpenIR
Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity
Chen, Tao ; Li, Hongmei ; Chen, Chen ; Wei, Lixin ; Li, Yulin
2017-07-01
发表期刊JOURNAL OF CHROMATOGRAPHIC SCIENCE
摘要Large-scale preparation and alpha-glucosidase inhibitory activity of a specific xanthone swertioside from Swertia mussotii were investigated in this study. Firstly, an efficient method was successfully established by liquid-liquid extraction, preparative high-performance liquid chromatography and sephadex LH-20 for large-scale preparation of swertioside. The recovery of swertioside reached 92.0%. Secondly, in vitro alpha-glucosidase inhibition experiment showed that swertioside had good inhibition close to acarbose. The study showed that swertioside had potential use as an anti-diabetic agent.
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/18053
专题中国科学院西北高原生物研究所
推荐引用方式
GB/T 7714
Chen, Tao,Li, Hongmei,Chen, Chen,et al. Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity[J]. JOURNAL OF CHROMATOGRAPHIC SCIENCE,2017.
APA Chen, Tao,Li, Hongmei,Chen, Chen,Wei, Lixin,&Li, Yulin.(2017).Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity.JOURNAL OF CHROMATOGRAPHIC SCIENCE.
MLA Chen, Tao,et al."Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity".JOURNAL OF CHROMATOGRAPHIC SCIENCE (2017).
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