New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus

NWIPB OpenIR

	New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus
	Wang, Yan-Ming ; Zhao, Jian-Qiang ; Zhou, Shuang-Yan ; Yang, Jun-Li ; Yao, Xiao-Jun ; Tao, Yan-Duo ; Mei, Li-Juan ; Shi, Yan-Ping
	2016-08-11
发表期刊	TETRAHEDRON
摘要	Phytochemical investigation on Asterothamnus centrali-asiaticus afforded four new sesquiterpenes, asterothamnones A-D (1-4), and three new benzofuran derivatives (5-7) together with ten known compounds (8-17). Their structures were elucidated using 1D and 2D NMR and X-ray diffraction analyses. Compounds 1-4 were verified to be unusual eudesmane sesquiterpenes possessing 4,6-dien-3-one or 1,4,6-triene-3-one conjugated system. The absolute configurations of compounds 1-8 were established by means of calculated electronic circular dichroism (ECD). Furthermore, all isolates were evaluated for their cytotoxic and anti-oxidant activities. Results showed that 10, 12 and, 14 exhibited cytotoxic activity against HepG2 cancer cells and 14 displayed cytotoxicity against MGC-803 cancer cells. Compounds 10 and 17 showed anti-oxidant effect. (C) 2016 Elsevier Ltd. All rights reserved.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/22724
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Wang, Yan-Ming,Zhao, Jian-Qiang,Zhou, Shuang-Yan,et al. New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus[J]. TETRAHEDRON,2016.
APA	Wang, Yan-Ming.,Zhao, Jian-Qiang.,Zhou, Shuang-Yan.,Yang, Jun-Li.,Yao, Xiao-Jun.,...&Shi, Yan-Ping.(2016).New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus.TETRAHEDRON.
MLA	Wang, Yan-Ming,et al."New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus".TETRAHEDRON (2016).