Analysis of five pharmacologically active compounds from Rhodiola for natural product drug discovery with capillary electrophoresis

NWIPB OpenIR

	Analysis of five pharmacologically active compounds from Rhodiola for natural product drug discovery with capillary electrophoresis
	Suo, YR ; Wang, HL ; Li, YL ; You, JM ; Wang, HQ
	2004-11-01
发表期刊	CHROMATOGRAPHIA ; Suo Yourui, Wang Honglun, Li Yulin, You Jinmao, Wang Haiqing.Analysis of five pharmacologically active compounds from Rhodiola for natural product drug discovery with capillary electrophoresis.CHROMATOGRAPHIA,2004,60(9-10):589-595
摘要	A rapid capillary electrophoresis method for the separation of five natural pharmacologically active compounds from extracted Rhodiola, namely salidroside, tyrosol, rhodionin, gallic acid and ethyl gallate has been developed. The separation of five natural pharmacologically active compounds was carried out in a fused-silica capillary with 14 mM boric acid, 30 mM SDS and 2.5% acetonitrile, adjusted to pH 10.7 with NaOH. Applied potential was 21 kV. The temperature of the capillary was maintained at 25 degreesC by the instrument thermostating system, with the correlation coefficients of 0.9805-0.9989 for migration time, and relative standards of < 3.52% for peak areas. The established method is rapid and reproducible for the separation of five natural pharmacologically compounds from extracts of Rhodiola with satisfactory results.; A rapid capillary electrophoresis method for the separation of five natural pharmacologically active compounds from extracted Rhodiola, namely salidroside, tyrosol, rhodionin, gallic acid and ethyl gallate has been developed. The separation of five natural pharmacologically active compounds was carried out in a fused-silica capillary with 14 mM boric acid, 30 mM SDS and 2.5% acetonitrile, adjusted to pH 10.7 with NaOH. Applied potential was 21 kV. The temperature of the capillary was maintained at 25 degreesC by the instrument thermostating system, with the correlation coefficients of 0.9805-0.9989 for migration time, and relative standards of < 3.52% for peak areas. The established method is rapid and reproducible for the separation of five natural pharmacologically compounds from extracts of Rhodiola with satisfactory results.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/25413
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Suo, YR,Wang, HL,Li, YL,et al. Analysis of five pharmacologically active compounds from Rhodiola for natural product drug discovery with capillary electrophoresis[J]. CHROMATOGRAPHIA, Suo Yourui, Wang Honglun, Li Yulin, You Jinmao, Wang Haiqing.Analysis of five pharmacologically active compounds from Rhodiola for natural product drug discovery with capillary electrophoresis.CHROMATOGRAPHIA,2004,60(9-10):589-595,2004.
APA	Suo, YR,Wang, HL,Li, YL,You, JM,&Wang, HQ.(2004).Analysis of five pharmacologically active compounds from Rhodiola for natural product drug discovery with capillary electrophoresis.CHROMATOGRAPHIA.
MLA	Suo, YR,et al."Analysis of five pharmacologically active compounds from Rhodiola for natural product drug discovery with capillary electrophoresis".CHROMATOGRAPHIA (2004).