Degradation of the potential rodent contraceptive quinestrol and elimination of its estrogenic activity in soil and water

NWIPB OpenIR

	Degradation of the potential rodent contraceptive quinestrol and elimination of its estrogenic activity in soil and water
	Zhang, Quan ; Wang, Cui ; Liu, Wanpeng ; Qu, Jiapeng ; Liu, Ming ; Zhang, Yanming ; Zhao, Meirong
	2014
发表期刊	ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH ; Zhang, Q; Wang, C; Liu, WP; Qu, JP; Liu, M; Zhang, YM; Zhao, MR.Degradation of the potential rodent contraceptive quinestrol and elimination of its estrogenic activity in soil and water,ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,2014,21(1):652
摘要	Quinestrol has shown potential for use in the fertility control of the plateau pika population of the Qinghai-Tibet Plateau. However, the environmental safety and fate of this compound are still obscure. Our study investigated degradation of quinestrol in a local soil and aquatic system for the first time. The results indicate that the degradation of quinestrol follows first-order kinetics in both soil and water, with a dissipation half-life of approximately 16.0 days in local soil. Microbial activity heavily influenced the degradation of quinestrol, with 41.2 % removal in non-sterile soil comparing to 4.8 % removal in sterile soil after incubation of 10 days. The half-lives in neutral water (pH 7.4) were 0.75 h when exposed to UV light (lambda = 365 nm) whereas they became 2.63 h when exposed to visible light (lambda > 400 nm). Acidic conditions facilitated quinestrol degradation in water with shorter half-lives of 1.04 and 1.47 h in pH 4.0 and pH 5.0 solutions, respectively. Moreover, both the soil and water treatment systems efficiently eliminated the estrogenic activity of quinestrol. Results presented herein clarify the complete degradation of quinestrol in a relatively short time. The ecological and environmental safety of this compound needs further investigation.; Quinestrol has shown potential for use in the fertility control of the plateau pika population of the Qinghai-Tibet Plateau. However, the environmental safety and fate of this compound are still obscure. Our study investigated degradation of quinestrol in a local soil and aquatic system for the first time. The results indicate that the degradation of quinestrol follows first-order kinetics in both soil and water, with a dissipation half-life of approximately 16.0 days in local soil. Microbial activity heavily influenced the degradation of quinestrol, with 41.2 % removal in non-sterile soil comparing to 4.8 % removal in sterile soil after incubation of 10 days. The half-lives in neutral water (pH 7.4) were 0.75 h when exposed to UV light (lambda = 365 nm) whereas they became 2.63 h when exposed to visible light (lambda > 400 nm). Acidic conditions facilitated quinestrol degradation in water with shorter half-lives of 1.04 and 1.47 h in pH 4.0 and pH 5.0 solutions, respectively. Moreover, both the soil and water treatment systems efficiently eliminated the estrogenic activity of quinestrol. Results presented herein clarify the complete degradation of quinestrol in a relatively short time. The ecological and environmental safety of this compound needs further investigation.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/27250
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Zhang, Quan,Wang, Cui,Liu, Wanpeng,et al. Degradation of the potential rodent contraceptive quinestrol and elimination of its estrogenic activity in soil and water[J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, Zhang, Q; Wang, C; Liu, WP; Qu, JP; Liu, M; Zhang, YM; Zhao, MR.Degradation of the potential rodent contraceptive quinestrol and elimination of its estrogenic activity in soil and water,ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,2014,21(1):652,2014.
APA	Zhang, Quan.,Wang, Cui.,Liu, Wanpeng.,Qu, Jiapeng.,Liu, Ming.,...&Zhao, Meirong.(2014).Degradation of the potential rodent contraceptive quinestrol and elimination of its estrogenic activity in soil and water.ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH.
MLA	Zhang, Quan,et al."Degradation of the potential rodent contraceptive quinestrol and elimination of its estrogenic activity in soil and water".ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2014).