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New monoterpenes from stalks and infructescence of Sibiraea leavigata
Zhao, Jian-Qiang ; Wang, Yan-Ming ; Lv, Jun-Jiang ; Wang, Shuo ; Mei, Li-Juan ; Tao, Yan-Duo
2016-12-01
发表期刊PHYTOCHEMISTRY LETTERS
摘要Chemical investigation of the ethanol extract of the stalks and infructescence of Sibiraea leavigata led to the isolation of two new monoterpenes named (4R)-2-(2-hydroxy-4-methyl-3-pentenyl) furan-2(5H)one (1) and (2R, 4R)-2-(2-hydroxyethyl)-4-(2-methyl-1-propenyl) furan-5H-2-one (2) along with eight known phenylpropanoids (3-10). Their structures were established on the basis of the interpretation of spectroscopic data and electronic circular dichroism (ECD) calculations. In addition, all of these isolates were evaluated for their cytotoxic activity. The results showed that compound 3 displayed moderate cytotoxicity with IC50 values ranging from 10.8 to 49.2 mu g mL(-1) against five cell lines. While 1 showed selective promotion effects on proliferation of gastric cancer MGC803 and RSC96 cell lines. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/27961
专题中国科学院西北高原生物研究所
推荐引用方式
GB/T 7714
Zhao, Jian-Qiang,Wang, Yan-Ming,Lv, Jun-Jiang,et al. New monoterpenes from stalks and infructescence of Sibiraea leavigata[J]. PHYTOCHEMISTRY LETTERS,2016.
APA Zhao, Jian-Qiang,Wang, Yan-Ming,Lv, Jun-Jiang,Wang, Shuo,Mei, Li-Juan,&Tao, Yan-Duo.(2016).New monoterpenes from stalks and infructescence of Sibiraea leavigata.PHYTOCHEMISTRY LETTERS.
MLA Zhao, Jian-Qiang,et al."New monoterpenes from stalks and infructescence of Sibiraea leavigata".PHYTOCHEMISTRY LETTERS (2016).
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