Microsatellite Mutation Rate during Allohexaploidization of Newly Resynthesized Wheat

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	Microsatellite Mutation Rate during Allohexaploidization of Newly Resynthesized Wheat
	Luo, Jiangtao 1; Hao, Ming 1; Zhang, Li 1; Chen, Jixiang 1; Zhang, Lianquan 1; Yuan, Zhongwei 1; Yan, Zehong 1; Zheng, Youliang 1; Zhang, Huaigang 2; Yen, Yang 3; Liu, Dengcai 1,2
	2012-10-01
发表期刊	INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
ISSN	1422-0067
卷号	13 期号:10 页码:12533-12543
文章类型	Article
摘要	Simple sequence repeats (SSRs, also known as microsatellites) are known to be mutational hotspots in genomes. DNA rearrangements have also been reported to accompany allopolyploidization. A study of the effect of allopolyploidization on SSR mutation is therefore important for understanding the origin and evolutionary dynamics of SSRs in allopolyploids. Three synthesized double haploid (SynDH) populations were made from 241 interspecific F-1 haploid hybrids between Triticum turgidum L. and Aegilops tauschii (Coss.) through spontaneous chromosome doubling via unreduced gametes. Mutation events were studied at 160 SSR loci in the S-1 generation (the first generation after chromosome doubling) of the three SynDH populations. Of the 148260 SSR alleles investigated in S-1 generation, only one mutation (changed number of repeats) was confirmed with a mutation rate of 6.74 x 10(-6). This mutation most likely occurred in the respective F-1 hybrid. In comparison with previously reported data, our results suggested that allohexaploidization of wheat did not increase SSR mutation rate.; Simple sequence repeats (SSRs, also known as microsatellites) are known to be mutational hotspots in genomes. DNA rearrangements have also been reported to accompany allopolyploidization. A study of the effect of allopolyploidization on SSR mutation is therefore important for understanding the origin and evolutionary dynamics of SSRs in allopolyploids. Three synthesized double haploid (SynDH) populations were made from 241 interspecific F-1 haploid hybrids between Triticum turgidum L. and Aegilops tauschii (Coss.) through spontaneous chromosome doubling via unreduced gametes. Mutation events were studied at 160 SSR loci in the S-1 generation (the first generation after chromosome doubling) of the three SynDH populations. Of the 148260 SSR alleles investigated in S-1 generation, only one mutation (changed number of repeats) was confirmed with a mutation rate of 6.74 x 10(-6). This mutation most likely occurred in the respective F-1 hybrid. In comparison with previously reported data, our results suggested that allohexaploidization of wheat did not increase SSR mutation rate.
关键词	Allopolyploidy Distant Hybridization Microsatellite Evolution Wheat
WOS标题词	Science & Technology ; Physical Sciences
关键词[WOS]	RAPID GENOMIC CHANGES ; HEXAPLOID WHEAT ; BRASSICA-NAPUS ; BREAD WHEAT ; CYTOSINE METHYLATION ; GENE-EXPRESSION ; EVOLUTION ; SEQUENCE ; LOCI ; ALLOPOLYPLOIDIZATION
收录类别	SCI
语种	英语
WOS研究方向	Chemistry
WOS类目	Chemistry, Multidisciplinary
WOS记录号	WOS:000310677800023
引用统计	被引频次：15[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/3600
专题	中国科学院西北高原生物研究所
作者单位	1.Sichuan Agr Univ, Triticeae Res Inst, Wenjiang 611130, Peoples R China 2.Chinese Acad Sci, NW Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810001, Peoples R China 3.S Dakota State Univ, Dept Biol & Microbiol, Brookings, SD 57007 USA
推荐引用方式 GB/T 7714	Luo, Jiangtao,Hao, Ming,Zhang, Li,et al. Microsatellite Mutation Rate during Allohexaploidization of Newly Resynthesized Wheat[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2012,13(10):12533-12543.
APA	Luo, Jiangtao.,Hao, Ming.,Zhang, Li.,Chen, Jixiang.,Zhang, Lianquan.,...&Liu, Dengcai.(2012).Microsatellite Mutation Rate during Allohexaploidization of Newly Resynthesized Wheat.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,13(10),12533-12543.
MLA	Luo, Jiangtao,et al."Microsatellite Mutation Rate during Allohexaploidization of Newly Resynthesized Wheat".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 13.10(2012):12533-12543.

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