Antioxidant xanthones from Swertia mussotii, a high altitude plant

NWIPB OpenIR

	Antioxidant xanthones from Swertia mussotii, a high altitude plant
	Luo, Cui-Ting ; Mao, Shuang-Shuang ; Liu, Fang-Lan ; Yang, Mao-xun ; Chen, Heru ; Kurihara, Hiroshi ; Li, Yulin ; Chen, HR (reprint author), Jinan Univ, Coll Pharm, Inst Tradit Chinese Med & Nat Prod, Huangpu Ave West 601, Guangzhou 510632, Guangdong, Peoples R China.
	2013-12-01
发表期刊	FITOTERAPIA ; Luo, CT; Mao, SS; Liu, FL; Yang, MX; Chen, HR; Kurihara, H; Li, YL.Antioxidant xanthones from Swertia mussotii, a high altitude plant,FITOTERAPIA,2013,91():140-147
摘要	Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-beta-D-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(beta-D-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(beta-D-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(beta-D-glucoside) (4), together with twenty-one known xanthones (5-25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORAC(FL) assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where I is the most active compound and 13 is the least one. A preliminary structure-activity relationship is also discussed. (C) 2013 Elsevier B.V. All rights reserved.; Four new xanthones, 3,5,6,8-tetrahydroxyxanthone-1-C-beta-D-glucoside (1), 7-hydroxy-3,4,8-trimethoxyxanthone-1-O-(beta-D-glucoside) (2), 6-hydroxy-3,5-dimethoxyxanthone-1-O-(beta-D-glucoside) (3), 3,4,7,8-tetramethoxyxanthone-1-O-(beta-D-glucoside) (4), together with twenty-one known xanthones (5-25) were isolated from the ethanol aqueous extract of Swertia mussotii. Their structures were elucidated via spectroscopic analyses. Oxygen radical absorbance capacity of all the isolated xanthones was systematically evaluated by ORAC(FL) assay. Results disclose that all the tested xanthones display moderate to excellent antioxidant activity, where I is the most active compound and 13 is the least one. A preliminary structure-activity relationship is also discussed. (C) 2013 Elsevier B.V. All rights reserved.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/37051
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Luo, Cui-Ting,Mao, Shuang-Shuang,Liu, Fang-Lan,et al. Antioxidant xanthones from Swertia mussotii, a high altitude plant[J]. FITOTERAPIA, Luo, CT; Mao, SS; Liu, FL; Yang, MX; Chen, HR; Kurihara, H; Li, YL.Antioxidant xanthones from Swertia mussotii, a high altitude plant,FITOTERAPIA,2013,91():140-147,2013.
APA	Luo, Cui-Ting.,Mao, Shuang-Shuang.,Liu, Fang-Lan.,Yang, Mao-xun.,Chen, Heru.,...&Chen, HR .(2013).Antioxidant xanthones from Swertia mussotii, a high altitude plant.FITOTERAPIA.
MLA	Luo, Cui-Ting,et al."Antioxidant xanthones from Swertia mussotii, a high altitude plant".FITOTERAPIA (2013).