Knowledge Management System of Northwest Institute of Plateau Biology, CAS
New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus | |
Wang, Yan-Ming ; Zhao, Jian-Qiang ; Zhou, Shuang-Yan ; Yang, Jun-Li ; Yao, Xiao-Jun ; Tao, Yan-Duo ; Mei, Li-Juan ; Shi, Yan-Ping | |
2016-08-11 | |
发表期刊 | TETRAHEDRON
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摘要 | Phytochemical investigation on Asterothamnus centrali-asiaticus afforded four new sesquiterpenes, asterothamnones A-D (1-4), and three new benzofuran derivatives (5-7) together with ten known compounds (8-17). Their structures were elucidated using 1D and 2D NMR and X-ray diffraction analyses. Compounds 1-4 were verified to be unusual eudesmane sesquiterpenes possessing 4,6-dien-3-one or 1,4,6-triene-3-one conjugated system. The absolute configurations of compounds 1-8 were established by means of calculated electronic circular dichroism (ECD). Furthermore, all isolates were evaluated for their cytotoxic and anti-oxidant activities. Results showed that 10, 12 and, 14 exhibited cytotoxic activity against HepG2 cancer cells and 14 displayed cytotoxicity against MGC-803 cancer cells. Compounds 10 and 17 showed anti-oxidant effect. (C) 2016 Elsevier Ltd. All rights reserved. |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/38012 |
专题 | 中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Wang, Yan-Ming,Zhao, Jian-Qiang,Zhou, Shuang-Yan,et al. New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus[J]. TETRAHEDRON,2016. |
APA | Wang, Yan-Ming.,Zhao, Jian-Qiang.,Zhou, Shuang-Yan.,Yang, Jun-Li.,Yao, Xiao-Jun.,...&Shi, Yan-Ping.(2016).New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus.TETRAHEDRON. |
MLA | Wang, Yan-Ming,et al."New sesquiterpenes and benzofuran derivatives from the aerial parts of Asterothamnus centrali-asiaticus".TETRAHEDRON (2016). |
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