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| Determination of Bisphenol A and Alkylphenols in Soft Drinks by High-Performance Liquid Chromatography with Fluorescence Detection | |
| Li, Yanxin1; Zhang, Shijuan2,3; Song, Cuihua1; You, Jinmao1; You, JM (reprint author), Qufu Normal Univ, Shandong Prov Key Lab Life Organ Anal, Coll Chem & Chem Engn, Qufu 273165, Peoples R China. | |
| 2013-10-01 | |
| 发表期刊 | FOOD ANALYTICAL METHODS
 |
| ISSN | 1936-9751 |
| 卷号 | 6期号:5页码:1284-1290 |
| 文章类型 | Article |
| 摘要 | A highly sensitive and selective method was developed for the purification and determination of bisphenol A and alkylphenols in soft drinks by using 2-(11H-benzo[a]carbazol-11-yl) ethyl chloroformate (BCEC-Cl) as pre-column labeling reagent followed by high-performance liquid chromatography (HPLC) with fluorescence detection. The HPLC sensitivity of bisphenol A and alkylphenols was greatly enhanced through the introduction of BCEC-Cl moiety with excellent fluorescence property into the target molecules. Meanwhile, the introduction of highly hydrophobic BCEC-Cl moiety into the analytes also greatly increased the hydrophobicity of the target compounds and distinguished them from hydrophilic matrices. Therefore, little interference was observed. Solid-phase extraction with C18 cartridges was applied to sample purification procedure with recoveries of higher than 82 %. When 20 mL of sample was used for analysis, the limits of quantifications of the analytes were between 0.06 and 0.1 mu g L-1. The proposed method was successfully applied to the determination of the target compounds in soft drink samples with a much higher sensitivity than traditional HPLC methods.; A highly sensitive and selective method was developed for the purification and determination of bisphenol A and alkylphenols in soft drinks by using 2-(11H-benzo[a]carbazol-11-yl) ethyl chloroformate (BCEC-Cl) as pre-column labeling reagent followed by high-performance liquid chromatography (HPLC) with fluorescence detection. The HPLC sensitivity of bisphenol A and alkylphenols was greatly enhanced through the introduction of BCEC-Cl moiety with excellent fluorescence property into the target molecules. Meanwhile, the introduction of highly hydrophobic BCEC-Cl moiety into the analytes also greatly increased the hydrophobicity of the target compounds and distinguished them from hydrophilic matrices. Therefore, little interference was observed. Solid-phase extraction with C18 cartridges was applied to sample purification procedure with recoveries of higher than 82 %. When 20 mL of sample was used for analysis, the limits of quantifications of the analytes were between 0.06 and 0.1 mu g L-1. The proposed method was successfully applied to the determination of the target compounds in soft drink samples with a much higher sensitivity than traditional HPLC methods. |
| 关键词 | Bisphenol a Alkylphenol Hplc Fluorescence |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| DOI | 10.1007/s12161-012-9541-0 |
| 关键词[WOS] | TANDEM MASS-SPECTROMETRY ; ENDOCRINE-DISRUPTING COMPOUNDS ; SOLID-PHASE EXTRACTION ; WASTE-WATER ; CANNED VEGETABLES ; LABELING REAGENT ; MILK ; GAS ; MICROEXTRACTION ; DERIVATIZATION |
| 收录类别 | SCI |
| 语种 | 英语 |
| 项目资助者 | Chinese Academy of Sciences(328) ; National Science Foundation of China(21275089) |
| WOS研究方向 | Food Science & Technology |
| WOS类目 | Food Science & Technology |
| WOS记录号 | WOS:000324271200006 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://210.75.249.4/handle/363003/3922 |
| 专题 | 中国科学院西北高原生物研究所 |
| 通讯作者 | You, JM (reprint author), Qufu Normal Univ, Shandong Prov Key Lab Life Organ Anal, Coll Chem & Chem Engn, Qufu 273165, Peoples R China. |
| 作者单位 | 1.Qufu Normal Univ, Shandong Prov Key Lab Life Organ Anal, Coll Chem & Chem Engn, Qufu 273165, Peoples R China 2.Chinese Acad Sci, Key Lab Adaptat & Evolut Plateau Biota, Northwest Plateau Inst Biol, Xining, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yanxin,Zhang, Shijuan,Song, Cuihua,et al. Determination of Bisphenol A and Alkylphenols in Soft Drinks by High-Performance Liquid Chromatography with Fluorescence Detection[J]. FOOD ANALYTICAL METHODS,2013,6(5):1284-1290. |
| APA | Li, Yanxin,Zhang, Shijuan,Song, Cuihua,You, Jinmao,&You, JM .(2013).Determination of Bisphenol A and Alkylphenols in Soft Drinks by High-Performance Liquid Chromatography with Fluorescence Detection.FOOD ANALYTICAL METHODS,6(5),1284-1290. |
| MLA | Li, Yanxin,et al."Determination of Bisphenol A and Alkylphenols in Soft Drinks by High-Performance Liquid Chromatography with Fluorescence Detection".FOOD ANALYTICAL METHODS 6.5(2013):1284-1290. |
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