Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)

NWIPB OpenIR

	Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)
	Li, Kexin ; Geng, Jianing ; Qu, Jiapeng ; Zhang, Yanming ; Hu, Songnian
	2010-11-10
发表期刊	BMC GENETICS ; Li, KX; Geng, JN; Qu, JP; Zhang, YM; Hu, SN.Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae),BMC GENETICS,2010,11():
摘要	Background: The plateau pika (Ochotona curzoniae) is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigree were used to validate the power of this set of markers. Results: The error in parentage assignment using a combination of these 10 loci was very low as indicated by their power of discrimination (0.803 - 0.932), power of exclusion (0.351 - 0.887), and an effectiveness of the combined probability of exclusion in parentage assignment of 99.999%. Conclusion: All the offspring of a family could be assigned to their biological mother; and their father or relatives could also be identified. This set of markers therefore provides a powerful and efficient tool for parentage assignment and other population analyses in the plateau pika.; Background: The plateau pika (Ochotona curzoniae) is an underground-dwelling mammal, native to the Tibetan plateau of China. A set of 10 polymorphic microsatellite loci has been developed earlier. Its reliability for parentage assignment has been tested in a plateau pika population. Two family groups with a known pedigree were used to validate the power of this set of markers.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/40873
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Li, Kexin,Geng, Jianing,Qu, Jiapeng,et al. Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)[J]. BMC GENETICS, Li, KX; Geng, JN; Qu, JP; Zhang, YM; Hu, SN.Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae),BMC GENETICS,2010,11():,2010.
APA	Li, Kexin,Geng, Jianing,Qu, Jiapeng,Zhang, Yanming,&Hu, Songnian.(2010).Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae).BMC GENETICS.
MLA	Li, Kexin,et al."Effectiveness of 10 polymorphic microsatellite markers for parentage and pedigree analysis in plateau pika (Ochotona curzoniae)".BMC GENETICS (2010).