Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry

NWIPB OpenIR

	Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry
	Li, Chunting 1,3; Liu, Yongqiang 2; Abdulla, Rahima 2; Aisa, Haji Akber 2; Suo, Yourui 1
	2014-06-07
发表期刊	ANALYTICAL METHODS
ISSN	1759-9660
卷号	6 期号:11 页码:3634-3643
文章类型	Article
摘要	Liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry (LC-ESI-QTOF-MS) was applied to identify chemical components occurring in Neopicrorhiza scrphulariiflora roots. 24 compounds, including 12 iridoid glycosides, 3 phenyl glycosides and 9 phenylethanoid glycosides, were detected and tentatively characterized according to accurate mass measurements and their characteristic fragmentation at low and high collision energy. Meanwhile, appropriate fragmentation pathways were proposed based on definite composition of the product ions. 6'-O-Feruloyl-3,4-dihydrocatalpol and 1-[2-(4-(3,4-dihydroxycinnamoyl)-3-glucosyl)glucosy]ethy-3-hydroxy-4-methoxybenzene are potentially novel compounds. 6'-O-Caffeoylcatalpol and maxoside were characterized in N. scrphulariiflora for the first time. This study established that the LC-ESI-QTOF-MS method is efficient for identifying, and could be the basis for the comprehensive quality control of, N. scrphulariiflora roots.; Liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry (LC-ESI-QTOF-MS) was applied to identify chemical components occurring in Neopicrorhiza scrphulariiflora roots. 24 compounds, including 12 iridoid glycosides, 3 phenyl glycosides and 9 phenylethanoid glycosides, were detected and tentatively characterized according to accurate mass measurements and their characteristic fragmentation at low and high collision energy. Meanwhile, appropriate fragmentation pathways were proposed based on definite composition of the product ions. 6'-O-Feruloyl-3,4-dihydrocatalpol and 1-[2-(4-(3,4-dihydroxycinnamoyl)-3-glucosyl)glucosy]ethy-3-hydroxy-4-methoxybenzene are potentially novel compounds. 6'-O-Caffeoylcatalpol and maxoside were characterized in N. scrphulariiflora for the first time. This study established that the LC-ESI-QTOF-MS method is efficient for identifying, and could be the basis for the comprehensive quality control of, N. scrphulariiflora roots.
WOS标题词	Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine ; Technology
关键词[WOS]	PICRORHIZA-SCROPHULARIIFLORA ; PHENYLETHANOID GLYCOSIDES ; STRUCTURAL-CHARACTERIZATION ; PHENYLPROPANOID GLYCOSIDES ; FLAVONOID GLYCOSIDES ; IRIDOID GLUCOSIDES ; MULTISTAGE ; FRAGMENTATION ; PHENYL
收录类别	SCI
语种	英语
WOS研究方向	Chemistry ; Food Science & Technology ; Spectroscopy
WOS类目	Chemistry, Analytical ; Food Science & Technology ; Spectroscopy
WOS记录号	WOS:000336820300015
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/4221
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Reg, Urumqi 830011, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Li, Chunting,Liu, Yongqiang,Abdulla, Rahima,et al. Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry[J]. ANALYTICAL METHODS,2014,6(11):3634-3643.
APA	Li, Chunting,Liu, Yongqiang,Abdulla, Rahima,Aisa, Haji Akber,&Suo, Yourui.(2014).Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry.ANALYTICAL METHODS,6(11),3634-3643.
MLA	Li, Chunting,et al."Characterization and identification of chemical components in Neopicrorhiza scrphulariiflora roots by liquid chromatography-electrospray ionization quadrupole time-of-flight tandem mass spectrometry".ANALYTICAL METHODS 6.11(2014):3634-3643.