NWIPB OpenIR
Application of an efficient strategy based on liquid-liquid extraction, high-speed counter-current chromatography, and preparative HPLC for the rapid enrichment, separation, and purification of four anthraquinones from Rheum tanguticum
Chen, Tao1; Liu, Yongling1,2; Zou, Denglang1,2; Chen, Chen1; You, Jinmao1; Zhou, Guoying1; Sun, Jing1; Li, Yulin1
2014
发表期刊JOURNAL OF SEPARATION SCIENCE
ISSN1615-9306
卷号37期号:1-2页码:165-170
文章类型Article
摘要This study presents an efficient strategy based on liquid-liquid extraction, high-speed counter-current chromatography, and preparative HPLC for the rapid enrichment, separation, and purification of four anthraquinones from Rheum tanguticum. A new solvent system composed of petroleum ether/ethyl acetate/water (4:2:1, v/v/v) was developed for the liquid-liquid extraction of the crude extract from R. tanguticum. As a result, emodin, aloe-emodin, physcion, and chrysophanol were greatly enriched in the organic layer. In addition, an efficient method was successfully established to separate and purify the above anthraquinones by high-speed counter-current chromatography and preparative HPLC. This study supplies a new alternative method for the rapid enrichment, separation, and purification of emodin, aloe-emodin, physcione, and chrysophanol.; This study presents an efficient strategy based on liquid-liquid extraction, high-speed counter-current chromatography, and preparative HPLC for the rapid enrichment, separation, and purification of four anthraquinones from Rheum tanguticum. A new solvent system composed of petroleum ether/ethyl acetate/water (4:2:1, v/v/v) was developed for the liquid-liquid extraction of the crude extract from R. tanguticum. As a result, emodin, aloe-emodin, physcion, and chrysophanol were greatly enriched in the organic layer. In addition, an efficient method was successfully established to separate and purify the above anthraquinones by high-speed counter-current chromatography and preparative HPLC. This study supplies a new alternative method for the rapid enrichment, separation, and purification of emodin, aloe-emodin, physcione, and chrysophanol.
关键词Anthraquinones High-speed Counter-current Chromatography Liquid-liquid Extraction Preparative Hplc Rheum Tanguticum
WOS标题词Science & Technology ; Physical Sciences
关键词[WOS]STILBENE GLYCOSIDES ; CONSTITUENTS ; PERFORMANCE ; CCC
收录类别SCI
语种英语
WOS研究方向Chemistry
WOS类目Chemistry, Analytical
WOS记录号WOS:000329478100024
引用统计
被引频次:33[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/4292
专题中国科学院西北高原生物研究所
作者单位1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810001, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Chen, Tao,Liu, Yongling,Zou, Denglang,et al. Application of an efficient strategy based on liquid-liquid extraction, high-speed counter-current chromatography, and preparative HPLC for the rapid enrichment, separation, and purification of four anthraquinones from Rheum tanguticum[J]. JOURNAL OF SEPARATION SCIENCE,2014,37(1-2):165-170.
APA Chen, Tao.,Liu, Yongling.,Zou, Denglang.,Chen, Chen.,You, Jinmao.,...&Li, Yulin.(2014).Application of an efficient strategy based on liquid-liquid extraction, high-speed counter-current chromatography, and preparative HPLC for the rapid enrichment, separation, and purification of four anthraquinones from Rheum tanguticum.JOURNAL OF SEPARATION SCIENCE,37(1-2),165-170.
MLA Chen, Tao,et al."Application of an efficient strategy based on liquid-liquid extraction, high-speed counter-current chromatography, and preparative HPLC for the rapid enrichment, separation, and purification of four anthraquinones from Rheum tanguticum".JOURNAL OF SEPARATION SCIENCE 37.1-2(2014):165-170.
条目包含的文件 下载所有文件
文件名称/大小 文献类型 版本类型 开放类型 使用许可
Application of an ef(516KB) 开放获取CC BY-NC-SA浏览 下载
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Chen, Tao]的文章
[Liu, Yongling]的文章
[Zou, Denglang]的文章
百度学术
百度学术中相似的文章
[Chen, Tao]的文章
[Liu, Yongling]的文章
[Zou, Denglang]的文章
必应学术
必应学术中相似的文章
[Chen, Tao]的文章
[Liu, Yongling]的文章
[Zou, Denglang]的文章
相关权益政策
暂无数据
收藏/分享
文件名: Application of an efficient strategy based on liquid–liquid extraction, high-speed counter-current chromatography, and preparative HPLC for the rapid enrichment, separation, and purificati.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。