NWIPB OpenIR
同位素编码衍生-分散液液微萃取/超高效液相色谱-串联质谱检测大鼠脑微透析液中儿茶酚胺
亓伟梅; 赵先恩; 亓永; 孙志伟; 陈光; 尤进茂; 索有瑞
2015
Source Publication分析测试学报
Issue9Pages:1014-1020
Subtype期刊论文
Abstract为实现微量大鼠脑微透析液中3种儿茶酚胺化合物的高灵敏检测,采用d0/d3-10-甲基-吖啶酮-2-磺酰氯(d0/d3-MASC)为同位素编码衍生化试剂,联合使用超声辅助分散液液微萃取技术,建立了超高效液相色谱-串联质谱(UHPLC-MS/MS)快速测定多巴胺(DA)、肾上腺素(EP)和去甲肾上腺素(NE)的分析方法。分别以d0-MASC和d3-MASC衍生微透析液样品和对照品,混合后采用分散液液微萃取技术富集净化,再进行UHPLC-MS/MS检测,以d3-MASC衍生物作为相应d0-MASC衍生物的内标物进行定量。结果表明,在p H 10.8乙腈水溶液中于37℃衍生反应3 min,即可实现待测...
Keyword活体微透析 帕金森病 多反应监测模式(Mrm) 稳定同位素标记
Funding Project西北高原生物研究所机构知识库
Document Type期刊论文
Identifierhttp://210.75.249.4/handle/363003/5326
Collection中国科学院西北高原生物研究所
Recommended Citation
GB/T 7714
亓伟梅,赵先恩,亓永,等. 同位素编码衍生-分散液液微萃取/超高效液相色谱-串联质谱检测大鼠脑微透析液中儿茶酚胺[J]. 分析测试学报,2015(9):1014-1020.
APA 亓伟梅.,赵先恩.,亓永.,孙志伟.,陈光.,...&索有瑞.(2015).同位素编码衍生-分散液液微萃取/超高效液相色谱-串联质谱检测大鼠脑微透析液中儿茶酚胺.分析测试学报(9),1014-1020.
MLA 亓伟梅,et al."同位素编码衍生-分散液液微萃取/超高效液相色谱-串联质谱检测大鼠脑微透析液中儿茶酚胺".分析测试学报 .9(2015):1014-1020.
Files in This Item: Download All
File Name/Size DocType Version Access License
同位素编码衍生_分散液液微萃取__省略_(867KB) 开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[亓伟梅]'s Articles
[赵先恩]'s Articles
[亓永]'s Articles
Baidu academic
Similar articles in Baidu academic
[亓伟梅]'s Articles
[赵先恩]'s Articles
[亓永]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[亓伟梅]'s Articles
[赵先恩]'s Articles
[亓永]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 同位素编码衍生_分散液液微萃取__省略_质谱检测大鼠脑微透析液中儿茶酚胺_亓伟梅.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.