Triterpenoids of Chrysosplenium carnosum

NWIPB OpenIR

	Triterpenoids of Chrysosplenium carnosum
	Lu, Meng-ya ; Liao, Zhi-xin ; Ji, Lan-ju ; Sun, Hong-fa
	2013-03-01
发表期刊	FITOTERAPIA
摘要	A phytochemical study of the ethanolic extract of Chrysosplenium carnosum Hook. f. et Thoms. led to the isolation of two new oleanane-type triterpenoids, 6 beta-hydroxy-3-oxoolean-12-en-27-oic acid (1) and 3 beta, 21 alpha-dihydroxyolean-12-en-27-oic acid (2), along with fourteen known compounds (3-16), all of which were isolated from this plant for the first time. The structures of these compounds were established on the basis of spectroscopic methods. Compounds 1-4 were evaluated for their in vitro anti-tumor activities on B16F10, SP2/0 and Hep-G2 cells lines. Compounds 1,3 and 4 exhibited strong inhibitory activity against B16F10 and SP2/0 cells' growth, compared with moderate cytotoxic activity against Hep-G2 cells. However, compound 2 showed to be inactive against these tumor cells. (C) 2013 Elsevier B.V. All rights reserved.
出版者	ELSEVIER SCIENCE BV
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/53442
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Lu, Meng-ya,Liao, Zhi-xin,Ji, Lan-ju,et al. Triterpenoids of Chrysosplenium carnosum[J]. FITOTERAPIA,2013.
APA	Lu, Meng-ya,Liao, Zhi-xin,Ji, Lan-ju,&Sun, Hong-fa.(2013).Triterpenoids of Chrysosplenium carnosum.FITOTERAPIA.
MLA	Lu, Meng-ya,et al."Triterpenoids of Chrysosplenium carnosum".FITOTERAPIA (2013).