Surveillance of Echinococcus isolates from Qinghai, China

NWIPB OpenIR

	Surveillance of Echinococcus isolates from Qinghai, China
	Ma, Junying 1; Wang, Hu 1; Lin, Gonghua 2; Zhao, Fang 2; Li, Chao 1; Zhang, Tongzuo 2; Ma, Xiao 1; Zhang, Yongguo 3; Hou, Zhibin 4; Cai, Huixia 1; Liu, Peiyun 1; Wang, Yongshun 1; Lin, GH (reprint author), Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810008, Peoples R China.
	2015-01-15
发表期刊	VETERINARY PARASITOLOGY
卷号	207 期号:1-2 页码:44-48
文章类型	Article
摘要	Echinococcosis is highly endemic over large parts of the Qinghai-Tibet Plateau (QTP), China. Based on a large number of samples, we present data on the current presence, host distribution, and genetic diversity of Echinococcus in the Qinghai Province, located in the northeastern corner of the QTP and constituting >25% of the area of the plateau. We used 521 samples (including 451 newly collected samples and 70 samples from our previous study) from humans, yaks, sheep, goats, dogs, fox, plateau pikas, and voles in 36 counties, and genotyped them using the mitochondrial DNA marker cytochrome oxidase subunit I (coxl) gene and the maximum parsimony and Bayesian reconstruction methods. Based on the 792 bp sequence matrix, we recorded 177 variable sites; 157 were parsimony-informative. A total of 105 haplotypes (H1-H105) were detected, of which H1-H15 and H90-H104, H16-H17, H18-H89, and H105 belonged to Echinococcus shiquicus, Echinococcus multilocularis,Echinococcus granulosus, and Echinococcus canadensis, respectively. Our results showed that, (i) the Qinghai Province was under a high burden of Echinococcus epidemiology; (ii) E. granulosus was the main echinococcosis threat to the local people, and the followed is E. multilocularis; (iii) there are a considerable number of haplotypes shared by domestic animals (sheep, yaks, and dogs) and humans, demonstrating the close relationship between human and domestic animals epidemiology; (iv) the threat of E. shiquicus on humans and livestock can be mostly ignored, while the infection risk of E. canadensis echinococcosis shquld not be neglected. (C) 2014 Elsevier B.V. All rights reserved.; Echinococcosis is highly endemic over large parts of the Qinghai-Tibet Plateau (QTP), China. Based on a large number of samples, we present data on the current presence, host distribution, and genetic diversity of Echinococcus in the Qinghai Province, located in the northeastern corner of the QTP and constituting >25% of the area of the plateau. We used 521 samples (including 451 newly collected samples and 70 samples from our previous study) from humans, yaks, sheep, goats, dogs, fox, plateau pikas, and voles in 36 counties, and genotyped them using the mitochondrial DNA marker cytochrome oxidase subunit I (coxl) gene and the maximum parsimony and Bayesian reconstruction methods. Based on the 792 bp sequence matrix, we recorded 177 variable sites; 157 were parsimony-informative. A total of 105 haplotypes (H1-H105) were detected, of which H1-H15 and H90-H104, H16-H17, H18-H89, and H105 belonged to Echinococcus shiquicus, Echinococcus multilocularis,Echinococcus granulosus, and Echinococcus canadensis, respectively. Our results showed that, (i) the Qinghai Province was under a high burden of Echinococcus epidemiology; (ii) E. granulosus was the main echinococcosis threat to the local people, and the followed is E. multilocularis; (iii) there are a considerable number of haplotypes shared by domestic animals (sheep, yaks, and dogs) and humans, demonstrating the close relationship between human and domestic animals epidemiology; (iv) the threat of E. shiquicus on humans and livestock can be mostly ignored, while the infection risk of E. canadensis echinococcosis shquld not be neglected. (C) 2014 Elsevier B.V. All rights reserved.
关键词	Echinococcus Qinghai Human Domestic Animal Coxl
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	TIBET PLATEAU ; GRANULOSUS ; POLYMORPHISM ; SHIQUICUS
收录类别	SCI
语种	英语
WOS研究方向	Parasitology ; Veterinary Sciences
WOS类目	Parasitology ; Veterinary Sciences
WOS记录号	WOS:000348949200005
引用统计	被引频次：34[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/5462
专题	中国科学院西北高原生物研究所
通讯作者	Lin, GH (reprint author), Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810008, Peoples R China.
作者单位	1.Qinghai Inst Endem Dis Prevent & Control, Xining 811602, Peoples R China 2.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810008, Peoples R China 3.Welf Char Hosp Qinghai Prov, Xining 810007, Peoples R China 4.Xining 2 Peoples Hosp Qinghai Prov, Xining 810003, Peoples R China
推荐引用方式 GB/T 7714	Ma, Junying,Wang, Hu,Lin, Gonghua,et al. Surveillance of Echinococcus isolates from Qinghai, China[J]. VETERINARY PARASITOLOGY,2015,207(1-2):44-48.
APA	Ma, Junying.,Wang, Hu.,Lin, Gonghua.,Zhao, Fang.,Li, Chao.,...&Lin, GH .(2015).Surveillance of Echinococcus isolates from Qinghai, China.VETERINARY PARASITOLOGY,207(1-2),44-48.
MLA	Ma, Junying,et al."Surveillance of Echinococcus isolates from Qinghai, China".VETERINARY PARASITOLOGY 207.1-2(2015):44-48.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
Ma-2015-Surveillance（594KB）			开放获取	CC BY-NC-SA	浏览下载