Pika Population Density Is Associated with the Composition and Diversity of Gut Microbiota

doi:10.3389/fmicb.2016.00758

NWIPB OpenIR

	Pika Population Density Is Associated with the Composition and Diversity of Gut Microbiota
	Li, Huan 1,2; Qu, Jiapeng 3; Li, Tongtong 1; Li, Jiabao 1; Lin, Qiang 1; Li, Xiangzhen 1
	2016-05-18
发表期刊	FRONTIERS IN MICROBIOLOGY
卷号	7
文章类型	Article
摘要	Host population density is positively associated with the strength of social interactions or the frequency of physical contacts, and thus potentially influences microbial transmission among individuals. However, the relationship between host density and gut microbiota remains unknown. Here, we characterized the gut microbiota of plateau pikas (Ochotona curzoniae) in wild experimental fields with different host population densities. The abundance of some gut microbes significantly correlated with host density, such as Ruminococcaceae, Lachnospiraceae, and Staphylococcaceae. Intriguingly, host density was positively correlated with alpha diversity (Shannon diversity and observed species) of gut microbial communities. The inter-individual gut microbiota within high-density groups were more similar to each other than those of low-density groups. Host density significantly explained the variations in the gut microbiota, even after controlling sex, weight, diet and geographical locations. Based on the PICRUSt metagenome prediction, positive correlations were observed between host density and the relative abundances of 12 gene functions involved in cellular processes, environmental information processing and metabolism. These results indicate the importance of host density as a factor in shaping gut microbial composition and diversity in plateau pikas, and may further help us understand the social transmission of gut microbiota.
关键词	Host Population Density Plateau Pika Gut Microbiota Composition Diversity
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.3389/fmicb.2016.00758
关键词[WOS]	RIBOSOMAL-RNA ; OCHOTONA-CURZONIAE ; COMMUNITIES ; SEQUENCES ; PLATEAU ; ECOLOGY ; RUMEN ; TRANSMISSION ; ABUNDANCE ; BACTERIA
收录类别	SCI
语种	英语
项目资助者	Natural Science Foundation of China(41371268 ; Open Found of Key Laboratory of Environmental and Applied Microbiology CAS(KLCAS-2016-03) ; 41450110074 ; 31300320 ; 41301272)
WOS研究方向	Microbiology
WOS类目	Microbiology
WOS记录号	WOS:000376003100001
引用统计	被引频次：96[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/5753
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Chengdu Inst Biol, Environm Microbiol Key Lab Sichuan Prov, Key Lab Environm & Appl Microbiol, Chengdu, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China 3.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining, Qinghai, Peoples R China
推荐引用方式 GB/T 7714	Li, Huan,Qu, Jiapeng,Li, Tongtong,et al. Pika Population Density Is Associated with the Composition and Diversity of Gut Microbiota[J]. FRONTIERS IN MICROBIOLOGY,2016,7.
APA	Li, Huan,Qu, Jiapeng,Li, Tongtong,Li, Jiabao,Lin, Qiang,&Li, Xiangzhen.(2016).Pika Population Density Is Associated with the Composition and Diversity of Gut Microbiota.FRONTIERS IN MICROBIOLOGY,7.
MLA	Li, Huan,et al."Pika Population Density Is Associated with the Composition and Diversity of Gut Microbiota".FRONTIERS IN MICROBIOLOGY 7(2016).