The synergistic effect of density stress during the maternal period and adulthood on immune traits of root vole (Microtus oeconomus) individuals-a field experiment

doi:10.1007/s00442-015-3445-9

NWIPB OpenIR

	The synergistic effect of density stress during the maternal period and adulthood on immune traits of root vole (Microtus oeconomus) individuals-a field experiment
	Du, Shou-Yang 1,3; Cao, Yi-Fan 1; Nie, Xu-Heng 1,3; Wu, Yan 2; Bian, Jiang-Hui 1
	2016-06-01
发表期刊	OECOLOGIA
卷号	181 期号:2 页码:335-346
文章类型	Article
摘要	The literature reveals that stress in early life or adulthood can influence immune function. As most studies on this are from the laboratory, there is a need for replicated studies in wild animals. This study aims to examine the effects of density stress during the maternal period and adulthood on immune traits of root vole (Microtus oeconomus) individuals. Four replicated high- and low-density parental populations were established, from which we obtained offspring and assigned each into four enclosures, two for each of the two density treatments used in establishing parental populations. The F1 offspring fecal corticosterone metabolite response to acute immobilization stress, anti-keyhole limpet hemocyanin immunoglobulin G (anti-KLH IgG) level, phytohemagglutinin (PHA)-delayed hypersensitivity and hematology at the end of the first breeding season, and prevalence and intensity of coccidial infection throughout the two breeding seasons, were tested. Density-induced maternally stressed offspring had delayed responses to acute immobilization stress. Density-stressed offspring as adults had reduced anti-KLH IgG levels and PHA responses, and the effects further deteriorated in maternally stressed offspring, leading to higher coccidial infection in the first breeding season than in the second. No correlations were found between immune traits or coccidial infection and survival over winter. These findings indicated that the combined density stresses during the maternal period and adulthood exhibited negative synergistic effects on immune traits. The synergistic effects lead to higher coccidial infection; however, this consequently reduced the risk of subsequent infection. The increased coccidial infection mediated by the synergistic effects may have an adaptive value in the context of the environment.
关键词	Coccidia Immunocompetence Maternal Stress Population Density Population Regulation
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1007/s00442-015-3445-9
关键词[WOS]	MICE PEROMYSCUS-MANICULATUS ; PRENATAL STRESS ; POPULATION REGULATION ; HUMORAL IMMUNITY ; TRADE-OFFS ; RATS ; ENVIRONMENT ; HORMONES ; SURVIVAL ; CORTICOSTERONE
收录类别	SCI
语种	英语
项目资助者	National Natural Science Foundation of China(31170394) ; Natural Science Foundation of Qinghai Province(2014-ZJ-913)
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Ecology
WOS记录号	WOS:000376296000002
引用统计	被引频次：8[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/5755
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810001, Peoples R China 2.Hangzhou Normal Univ, Sch Life & Environm Sci, Hangzhou 310012, Zhejiang, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Du, Shou-Yang,Cao, Yi-Fan,Nie, Xu-Heng,et al. The synergistic effect of density stress during the maternal period and adulthood on immune traits of root vole (Microtus oeconomus) individuals-a field experiment[J]. OECOLOGIA,2016,181(2):335-346.
APA	Du, Shou-Yang,Cao, Yi-Fan,Nie, Xu-Heng,Wu, Yan,&Bian, Jiang-Hui.(2016).The synergistic effect of density stress during the maternal period and adulthood on immune traits of root vole (Microtus oeconomus) individuals-a field experiment.OECOLOGIA,181(2),335-346.
MLA	Du, Shou-Yang,et al."The synergistic effect of density stress during the maternal period and adulthood on immune traits of root vole (Microtus oeconomus) individuals-a field experiment".OECOLOGIA 181.2(2016):335-346.