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Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity | |
Chen, Tao ; Li, Hongmei ; Chen, Chen ; Wei, Lixin ; Li, Yulin | |
2017-07-01 | |
发表期刊 | JOURNAL OF CHROMATOGRAPHIC SCIENCE |
摘要 | Large-scale preparation and alpha-glucosidase inhibitory activity of a specific xanthone swertioside from Swertia mussotii were investigated in this study. Firstly, an efficient method was successfully established by liquid-liquid extraction, preparative high-performance liquid chromatography and sephadex LH-20 for large-scale preparation of swertioside. The recovery of swertioside reached 92.0%. Secondly, in vitro alpha-glucosidase inhibition experiment showed that swertioside had good inhibition close to acarbose. The study showed that swertioside had potential use as an anti-diabetic agent. |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/58773 |
专题 | 中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Chen, Tao,Li, Hongmei,Chen, Chen,et al. Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity[J]. JOURNAL OF CHROMATOGRAPHIC SCIENCE,2017. |
APA | Chen, Tao,Li, Hongmei,Chen, Chen,Wei, Lixin,&Li, Yulin.(2017).Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity.JOURNAL OF CHROMATOGRAPHIC SCIENCE. |
MLA | Chen, Tao,et al."Large-Scale Preparation of a Specific Xanthone from Swertia mussotii and Evaluation of Its alpha-Glucosidase Inhibitory Activity".JOURNAL OF CHROMATOGRAPHIC SCIENCE (2017). |
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