Aggregation-induced emission of copper nanoclusters triggered by synergistic effect of dual metal ions and the application in the detection of H2O2 and related biomolecules

NWIPB OpenIR

	Aggregation-induced emission of copper nanoclusters triggered by synergistic effect of dual metal ions and the application in the detection of H2O2 and related biomolecules
	Qu, Fei; Yang, Qianqian; Wang, Bingjie; You, Jinmao
	2020
发表期刊	TALANTA
卷号	207
摘要	Recently, the aggregation-induced emission (AIE) of nanoclusters triggered by metal ions has been received great attentions. However, the good AIE efficiency usually requires excessive metal ions, which may result in an undesired competition between metal ions and targets. In this work, by the synergistic effect of Pb2+ and Zr4+, a fewer amounts of metal ions can induce more aggregates of glutathione-capped Cu nanoclusters (CSH-CuNCs), resulting in a higher AIE efficiency. Next, by virtue of the oxidative property of H2O2, the AIE of GSH-CuNCs-Pb2+-Zr4+ system quenches linearly with the concentration of H2O2 from 1 to 60 mu mol/L. Moreover, many biological substrates, such as glucose and cholesterol, can generate H2O2 in the presence of their specific oxi-dases and O-2. Therefore, the detection of glucose or cholesterol can also be achieved by the proposed method, and the limits of detection of glucose and cholesterol are 0.37 and 2.7 mu mol/L, respectively. Finally, this method has been validated to be sensitive and selective for glucose or cholesterol detection in human serum samples.
关键词	Copper nanoclusters Aggregation induced emission Zr4+ Pb2+ H2O2
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/59668
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Qu, Fei,Yang, Qianqian,Wang, Bingjie,et al. Aggregation-induced emission of copper nanoclusters triggered by synergistic effect of dual metal ions and the application in the detection of H2O2 and related biomolecules[J]. TALANTA,2020,207.
APA	Qu, Fei,Yang, Qianqian,Wang, Bingjie,&You, Jinmao.(2020).Aggregation-induced emission of copper nanoclusters triggered by synergistic effect of dual metal ions and the application in the detection of H2O2 and related biomolecules.TALANTA,207.
MLA	Qu, Fei,et al."Aggregation-induced emission of copper nanoclusters triggered by synergistic effect of dual metal ions and the application in the detection of H2O2 and related biomolecules".TALANTA 207(2020).