Environmental filtering increases with elevation for the assembly of gut microbiota in wild pikas

NWIPB OpenIR

	Environmental filtering increases with elevation for the assembly of gut microbiota in wild pikas
	Li, Huan; Zhou, Rui; Zhu, Jianxiao; Huang, Xiaodan; Qu, Jiapeng
	2019
发表期刊	MICROBIAL BIOTECHNOLOGY
卷号	12 期号:5
摘要	Despite their important roles in host nutrition, metabolism and adaptability, the knowledge on how the mammalian gut microbial community assemble is relatively scanty, especially regarding the ecological mechanisms that govern microbiota along environmental gradients. To address this, we surveyed the diversity, function and ecological processes of gut microbiota in the wild plateau pika, Ochotona curzoniae, along the elevational gradient from 3106 to 4331 m on 'the Roof of the World'-Qinghai-Tibet Plateau. The results indicated that the alpha, beta and functional diversity of gut microbiota significantly increased with elevation, and elevation significantly explained the variations in the gut microbial communities, even after controlling for geographical distance, host sex and body weight. Some gene functions (e.g. nitrogen metabolism and protein kinases) associated with metabolism were enriched in the high-altitude pikas. Null model and phylogenetic analysis suggest that the relative contributions of environmental filtering responsible for local gut communities increased with elevation. In addition, deterministic processes dominated gut microbial communities in the high-altitude (more than 3694 m) pikas, while the percentages of stochastic and deterministic processes were very close in the low-altitude (3106 and 3580 m) pikas. The observed mechanisms that influence pika gut microbiota assembly and function seemed to be mainly mediated by the internal gut environment and by the external environmental pressure (i.e. lower temperature) in the harsh high-altitude environment. These findings enhance our understanding of gut microbiota assembly patterns and function in wild mammals from extreme harsh environments.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/59717
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Li, Huan,Zhou, Rui,Zhu, Jianxiao,et al. Environmental filtering increases with elevation for the assembly of gut microbiota in wild pikas[J]. MICROBIAL BIOTECHNOLOGY,2019,12(5).
APA	Li, Huan,Zhou, Rui,Zhu, Jianxiao,Huang, Xiaodan,&Qu, Jiapeng.(2019).Environmental filtering increases with elevation for the assembly of gut microbiota in wild pikas.MICROBIAL BIOTECHNOLOGY,12(5).
MLA	Li, Huan,et al."Environmental filtering increases with elevation for the assembly of gut microbiota in wild pikas".MICROBIAL BIOTECHNOLOGY 12.5(2019).