Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds

NWIPB OpenIR

	Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds
	Wu, Jiyao; Wang, Jianjin; Yue, Binglin; Fang Xing-tang; Zhang, Chunlei; Ma, Yun; Hu, Linyong; Bai, Yueyu; Qi, Xingshan; Chen, Hong
	2019
发表期刊	ANIMAL BIOTECHNOLOGY
卷号	30 期号:3
摘要	The objective of this study was to examine the association of transient receptor potential vanilloid 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1) genes polymorphisms with growth traits in three Chinese cattle breeds (Jiaxian red cattle, Qinchuan cattle and Luxi cattle). Through experiments we identified three single nucleotide polymorphisms (SNPs) in these three cattle breeds TRPV1 and TRPA1 genes using PCR-SSCP, (forced) PCR-RFLP methods. Three of these polymorphisms are all synonymous mutation which includes (NW_003104493.1: 30327 C > T), (NW_003104493.1: 33394 A > G) and (NW_003104493.1: 38471 G > A) are in exons. The other three polymorphisms are located at 3'UTR. Furthermore, we evaluated the haplotype frequency and the statistical analyses indicated that these SNPs of TRPV1 and TRPA1 genes were associated with bovine body height, body length, waist angle width, hucklebone width, cross ministry height, chest qingwidth (p < 0.05) and recommendation height, cannon circumference (p < 0.01) of Qingchuan cattle; body length, waist angle width (p < 0.05) of Jiaxian red cattle; body weight, Body length, cannon circumference, chest circumference (p < 0.05) and body height (p < 0.01) of Luxi cattle. Our result confirms the polymorphisms in the TRPV1 and TRPA1 genes are associated with growth traits that may be used for marker-assisted selection (MAS) in three beef breeds programs.
关键词	TRPV1 and TRPA1 SNPs growth traits polymorphism cattle
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/59750
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Wu, Jiyao,Wang, Jianjin,Yue, Binglin,et al. Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds[J]. ANIMAL BIOTECHNOLOGY,2019,30(3).
APA	Wu, Jiyao.,Wang, Jianjin.,Yue, Binglin.,Fang Xing-tang.,Zhang, Chunlei.,...&Chen, Hong.(2019).Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds.ANIMAL BIOTECHNOLOGY,30(3).
MLA	Wu, Jiyao,et al."Research on association between variants and haplotypes of TRPV1 and TRPA1 genes with growth traits in three cattle breeds".ANIMAL BIOTECHNOLOGY 30.3(2019).