TBAF-Catalyzed O-Nucleophilic Cyclization of Enaminones: A Process for the Synthesis of Dihydroisobenzofuran Derivatives

NWIPB OpenIR

	TBAF-Catalyzed O-Nucleophilic Cyclization of Enaminones: A Process for the Synthesis of Dihydroisobenzofuran Derivatives
	Zhao, Yulei; Zhang, Zheng; Liu, Xu; Wang, Zongkang; Cao, Ziping; Tian, Laijin; Yue, Mingbo; You, Jinmao
	2019
发表期刊	JOURNAL OF ORGANIC CHEMISTRY
卷号	84 期号:3
摘要	A novel methodology for the stereoselective synthesis of dihydroisobenzofuran derivatives is described in this paper. The procedure was realized by the bifunctional TBAF catalyzed selective O-nucleophilic cyclization of enaminone with intramolecular alkyne under mild and non-metal-mediated conditions. The results of control experiments suggested that the cation-pi interaction and basicity, offered by TBAF, might be indispensable for the isomerization of enaminone and the formation of carbon-oxygen bond.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/59866
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Zhao, Yulei,Zhang, Zheng,Liu, Xu,et al. TBAF-Catalyzed O-Nucleophilic Cyclization of Enaminones: A Process for the Synthesis of Dihydroisobenzofuran Derivatives[J]. JOURNAL OF ORGANIC CHEMISTRY,2019,84(3).
APA	Zhao, Yulei.,Zhang, Zheng.,Liu, Xu.,Wang, Zongkang.,Cao, Ziping.,...&You, Jinmao.(2019).TBAF-Catalyzed O-Nucleophilic Cyclization of Enaminones: A Process for the Synthesis of Dihydroisobenzofuran Derivatives.JOURNAL OF ORGANIC CHEMISTRY,84(3).
MLA	Zhao, Yulei,et al."TBAF-Catalyzed O-Nucleophilic Cyclization of Enaminones: A Process for the Synthesis of Dihydroisobenzofuran Derivatives".JOURNAL OF ORGANIC CHEMISTRY 84.3(2019).