Highly selective metal-organic framework-based sensor for protamine through photoinduced electron transfer

NWIPB OpenIR

	Highly selective metal-organic framework-based sensor for protamine through photoinduced electron transfer
	Qu, Fei; Li, Xiaonan; Lv, Xiaoxia; You, Jinmao; Han, Wenli
	2019
发表期刊	JOURNAL OF MATERIALS SCIENCE
卷号	54 期号:4
摘要	Photoinduced electron transfer (PET) has been used as reporter in the field of photoluminescence sensors and switches, and intermolecular PET is believed to be responsible for fluorescence quenching. Herein, the emissions of Tb-MOF can be quenched effectively by protamine based on PET. Compared with conventional electrostatic attraction mechanism, this approach suffers less interference from other charged substances and has a broader linear range of protamine from 3 to 5000ng/mL with limit of detection (LOD) 1.21ng/mL. Subsequently, the strong binding effect of protamine toward Hep ascribed to electrostatic attraction hinders the interaction between Tb-MOF and protamine, resulting in the high emissions of framework. The detection of Hep also shows a good linear range from 0.5 to 5M with LOD 0.27M. Finally, this novel probe is also successfully applied to the determination of protamine and Hep in human serum with satisfactory results.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/59870
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Qu, Fei,Li, Xiaonan,Lv, Xiaoxia,et al. Highly selective metal-organic framework-based sensor for protamine through photoinduced electron transfer[J]. JOURNAL OF MATERIALS SCIENCE,2019,54(4).
APA	Qu, Fei,Li, Xiaonan,Lv, Xiaoxia,You, Jinmao,&Han, Wenli.(2019).Highly selective metal-organic framework-based sensor for protamine through photoinduced electron transfer.JOURNAL OF MATERIALS SCIENCE,54(4).
MLA	Qu, Fei,et al."Highly selective metal-organic framework-based sensor for protamine through photoinduced electron transfer".JOURNAL OF MATERIALS SCIENCE 54.4(2019).