Emericelactones A-D: Four novel polyketides produced by Emericella sp. XL.029, a fungus associated the leaves of Panax notoginseng

NWIPB OpenIR

	Emericelactones A-D: Four novel polyketides produced by Emericella sp. XL.029, a fungus associated the leaves of Panax notoginseng
	Pang, Xue-Jiao; Zhang, Shuai-Bing; Chen, Hai-Li; Zhao, Wen-Ting; Yang, Deng-Feng; Xian, Peng-Jie; Xu, Lu-Lin; Tao, Yan-Duo; Fu, Hai-Yan; Yang, Xiao-Long
	2018
发表期刊	TETRAHEDRON LETTERS
卷号	59 期号:52
摘要	The application of an OSMAC approach on an endophytic fungus Emericella sp. XL 029 has yielded four novel polyketides, emericelactones A-D (1-4). The structures and stereochemistry of 1-4 were elucidated by NMR and MS data analyses, computational methods, as well as by comparison with known compounds. Compound 1 contained an unprecedented linear pentaene substructure ending in an oxabicyclo[2.2.1 ]heptane moiety, while compounds 2-4 are epimers possessing an unprecedented linear triene structures ending in two cyclic moieties of an oxabicyclo[2.2.1 ]heptane and a cyclopentan-l-one. Compounds 1-4 showed moderate antimicrobial activities against three agricultural pathogenic fungi (Verticillium dahliae Kleb, Rhizoctonia solani and Gibberella saubinetii) and two human pathogenic bacteria (Micro coccus lysodeikticus and Salmonella typhi) with MIC values of 25-50 mu g/mL. (C) 2018 Elsevier Ltd. All rights reserved.
关键词	Panax notoginseng Emericella sp. Polyketide Antimicrobial activity
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/59911
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Pang, Xue-Jiao,Zhang, Shuai-Bing,Chen, Hai-Li,et al. Emericelactones A-D: Four novel polyketides produced by Emericella sp. XL.029, a fungus associated the leaves of Panax notoginseng[J]. TETRAHEDRON LETTERS,2018,59(52).
APA	Pang, Xue-Jiao.,Zhang, Shuai-Bing.,Chen, Hai-Li.,Zhao, Wen-Ting.,Yang, Deng-Feng.,...&Yang, Xiao-Long.(2018).Emericelactones A-D: Four novel polyketides produced by Emericella sp. XL.029, a fungus associated the leaves of Panax notoginseng.TETRAHEDRON LETTERS,59(52).
MLA	Pang, Xue-Jiao,et al."Emericelactones A-D: Four novel polyketides produced by Emericella sp. XL.029, a fungus associated the leaves of Panax notoginseng".TETRAHEDRON LETTERS 59.52(2018).