Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017)

NWIPB OpenIR

	Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017)
	Kurskaya, Olga; Ryabichenko, Tatyana; Leonova, Natalya; Shi, Weifeng; Bi, Hongtao; Sharshov, Kirill; Kazachkova, Eugenia; Sobolev, Ivan; Prokopyeva, Elena; Kartseva, Tatiana; Alekseev, Alexander; Shestopalov, Alexander
	2018
发表期刊	PLOS ONE
卷号	13 期号:9
摘要	Background Acute respiratory infections (ARIs) cause a considerable morbidity and mortality worldwide especially in children. However, there are few studies of the etiological structure of ARIs in Russia. In this work, we analyzed the etiology of ARIs in children (0-15 years old) admitted to Novosibirsk Children's Municipal Clinical Hospital in 2013-2017. Methods We tested nasal and throat swabs of 1560 children with upper or lower respiratory infection for main respiratory viruses (influenza viruses A and B, parainfluenza virus types 1-4, respiratory syncytial virus, metapneumovirus, four human coronaviruses, rhinovirus, adenovirus and bocavirus) using a RT-PCR Kit. Results We detected 1128 (72.3%) samples were positive for at least one virus. The most frequently detected pathogens were respiratory syncytial virus (358/1560, 23.0%), influenza virus (344/1560, 22.1%), and rhinovirus (235/1560, 15.1%). Viral co-infections were found in 163 out of the 1128 (14.5%) positive samples. We detected significant decrease of the respiratory syncytial virus-infection incidence in children with increasing age, while the reverse relationship was observed for influenza viruses. Conclusions We evaluated the distribution of respiratory viruses in children with ARIs and showed the prevalence of respiratory syncytial virus and influenza virus in the etiological structure of infections. This study is important for the improvement and optimization of diagnostic tactics, control and prevention of the respiratory viral infections.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/59967
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Kurskaya, Olga,Ryabichenko, Tatyana,Leonova, Natalya,et al. Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017)[J]. PLOS ONE,2018,13(9).
APA	Kurskaya, Olga.,Ryabichenko, Tatyana.,Leonova, Natalya.,Shi, Weifeng.,Bi, Hongtao.,...&Shestopalov, Alexander.(2018).Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017).PLOS ONE,13(9).
MLA	Kurskaya, Olga,et al."Viral etiology of acute respiratory infections in hospitalized children in Novosibirsk City, Russia (2013-2017)".PLOS ONE 13.9(2018).