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Cu2+modulated DNA- templated silver nanoclusters as a turn- on fluorescence probe for the detection of quinolones
Wang, Renjun; Yan, Xiaolu; Sun, Jing; Wang, Xiao; Zhao, Xian-En; Liu, Wei; Zhu, Shuyun
2018
发表期刊ANALYTICAL METHODS
卷号10期号:34
摘要In this contribution, DNA-templated silver nanoclusters (DNA-AgNCs) were successfully utilized as novel fluorescent probes for the detection of quinolones for the first time. The as-prepared DNA-AgNCs exhibited strong emission at 596 nm, which could be quenched by Cu2+ ions. The addition of quinolones caused restoration of fluorescence intensity of the DNA-AgNCs-Cu2+ system. This detection protocol exhibited excellent sensitivities for four kinds of quinolones. For instance, the linear ranges were from 20 to 100 nM for nalidixic acid with the limit of detection (LOD) 2.0 nM, from 5 to 120 nM for cinoxacin with the LOD 1.2 nM, from 5 to 100 nM for ciprofloxacin with the LOD 1.0 nM, and from 1 to 60 nM for moxifloxacin with the LOD 96 pM, respectively. Benefiting from high sensitivity, satisfactory recoveries were obtained for trace detection of quinolones in real samples, such as tablets and human urine.
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/59971
专题中国科学院西北高原生物研究所
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GB/T 7714
Wang, Renjun,Yan, Xiaolu,Sun, Jing,et al. Cu2+modulated DNA- templated silver nanoclusters as a turn- on fluorescence probe for the detection of quinolones[J]. ANALYTICAL METHODS,2018,10(34).
APA Wang, Renjun.,Yan, Xiaolu.,Sun, Jing.,Wang, Xiao.,Zhao, Xian-En.,...&Zhu, Shuyun.(2018).Cu2+modulated DNA- templated silver nanoclusters as a turn- on fluorescence probe for the detection of quinolones.ANALYTICAL METHODS,10(34).
MLA Wang, Renjun,et al."Cu2+modulated DNA- templated silver nanoclusters as a turn- on fluorescence probe for the detection of quinolones".ANALYTICAL METHODS 10.34(2018).
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