NWIPB OpenIR
Simultaneous Detection of Adenosine Triphosphate and Glucose Based on the Cu-Fenton Reaction
Qu, Fei; Li, Jingwen; Han, Wenli; Xia, Lian; You, Jinmao
2018
发表期刊SENSORS
卷号18期号:7
摘要Both adenosine triphosphate (ATP) and glucose are important to human health, and their abnormal levels are closely related to angiocardiopathy and hypoglycaemia. Therefore, the simultaneous determination of ATP and glucose with a single test mode is highly desirable for disease diagnostics and early recognition. Herein, a new fluorescence on/off switch sensing platform is developed by carbon nanodots (CNDs) to detect ATP and glucose simultaneously. The fluorescence of CNDs can be quenched by Cu2+ and hydrogen peroxide (H2O2), due to the formation of hydroxyl radicals (center dot OH) produced in the Cu-Fenton reaction. Based on the high affinity of Cu2+ with ATP, the fluorescence of CNDs will recover effectively after adding ATP. Additionally, glucose can be efficiently catalyzed by glucose oxidase (GOx) to generate H2O2, so the platform can also be utilized to analyze glucose. Under optimum conditions, this sensing platform displays excellent sensitivity and the linear ranges are from 0.1 to 7 mu M for ATP with a limit of detection (LOD) of 30.2 nM, and from 0.1 to 7 mM for glucose with a LOD 39.8 mu M, respectively. Benefiting from the high sensitivity and selectivity, this sensing platform is successfully applied for simultaneous detection of ATP and glucose in human serum samples with satisfactory recoveries.
关键词simultaneous detection Cu-Fenton reaction carbon nanodots adenosine triphosphate glucose satisfactory recoveries
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/60006
专题中国科学院西北高原生物研究所
推荐引用方式
GB/T 7714
Qu, Fei,Li, Jingwen,Han, Wenli,et al. Simultaneous Detection of Adenosine Triphosphate and Glucose Based on the Cu-Fenton Reaction[J]. SENSORS,2018,18(7).
APA Qu, Fei,Li, Jingwen,Han, Wenli,Xia, Lian,&You, Jinmao.(2018).Simultaneous Detection of Adenosine Triphosphate and Glucose Based on the Cu-Fenton Reaction.SENSORS,18(7).
MLA Qu, Fei,et al."Simultaneous Detection of Adenosine Triphosphate and Glucose Based on the Cu-Fenton Reaction".SENSORS 18.7(2018).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Qu, Fei]的文章
[Li, Jingwen]的文章
[Han, Wenli]的文章
百度学术
百度学术中相似的文章
[Qu, Fei]的文章
[Li, Jingwen]的文章
[Han, Wenli]的文章
必应学术
必应学术中相似的文章
[Qu, Fei]的文章
[Li, Jingwen]的文章
[Han, Wenli]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。