Convenient and sensitive colorimetric determination of alendronate sodium with Ce4+-triggered oxidation of TMB

NWIPB OpenIR

	Convenient and sensitive colorimetric determination of alendronate sodium with Ce4+-triggered oxidation of TMB
	Sun, Jing; Wang, Rui; Xia, Meng; Zhu, Shuyun; Zhao, Xian-En
	2020
发表期刊	NEW JOURNAL OF CHEMISTRY
卷号	44 期号:30
摘要	As alternatives to nanozymes, some metal ions have been used in chemical/biochemical sensors owing to their facile acquisition avoiding tedious preparation and purification. Ce(4+)has been reported to possess oxidase-like activity. Ascribed to its strong oxidative ability, Ce(4+)can trigger the oxidation of 3,3 ',5,5 '-tetramethylbenzidine (TMB) to its blue product oxTMB without the requirement of H2O2. When ALDS is added, the oxidation ability of Ce(4+)can be reduced because of the redox reaction between Ce(4+)and ALDS. The absorbance intensity ascribed to oxTMB decreases followed by the fading of the solution. On the basis of such a mechanism, a simple method is proposed for monitoring ALDS in two linear ranges of 0.1-10.0 mu M and 10.0-60.0 mu M. The detection limit is low to 0.05 mu M. Furthermore, this method exhibits great potential for ALDS detection in real biological body fluids and pharmaceutical samples.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/60276
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Sun, Jing,Wang, Rui,Xia, Meng,et al. Convenient and sensitive colorimetric determination of alendronate sodium with Ce4+-triggered oxidation of TMB[J]. NEW JOURNAL OF CHEMISTRY,2020,44(30).
APA	Sun, Jing,Wang, Rui,Xia, Meng,Zhu, Shuyun,&Zhao, Xian-En.(2020).Convenient and sensitive colorimetric determination of alendronate sodium with Ce4+-triggered oxidation of TMB.NEW JOURNAL OF CHEMISTRY,44(30).
MLA	Sun, Jing,et al."Convenient and sensitive colorimetric determination of alendronate sodium with Ce4+-triggered oxidation of TMB".NEW JOURNAL OF CHEMISTRY 44.30(2020).