Subcritical Water Extraction of Sesquiterpene Lactones from Inula racemose

NWIPB OpenIR

	Subcritical Water Extraction of Sesquiterpene Lactones from Inula racemose
	Chi, Xiaofeng; Zhang, Guoying; Chen, Shilong
	2020
发表期刊	CHEMISTRYSELECT
卷号	5 期号:2
摘要	Inula racemose, a traditional Tibetan medicine with strong antifungal and anti-inflammatory activities, contains large amounts of sesquiterpene lactones. In the current study, subcritical water extraction was employed for the efficient extraction sesquiterpene lactones from I. racemose. Various parameters, such as extraction time (23.2-56.8 min), temperature (129.5-230.5 degrees C) and SW flow rate (1.3-4.7 mL/min) was investigated for optimizing the recovery of the targeted compounds. The optimal conditions for SWE were determined as follows: extraction time of 45 min, extraction temperature of 190 degrees C, and SW flow rate of 3.0 mL/min, and a recovery of 71.97% was achieved. Four sesquiterpene lactone isomers were separated by prep-HPLC from the SWE extract and identified as igalan, isoalantolactone, alantolactone, and alloantolactone. A comparison of SWE with traditional extraction technologies showed that subcritical water could be a green and efficient substitution for the extraction of sesquiterpene lactones from I. racemose.
关键词	Inula racemose Sesquiterpene lactones Subcritical water extraction
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/60438
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Chi, Xiaofeng,Zhang, Guoying,Chen, Shilong. Subcritical Water Extraction of Sesquiterpene Lactones from Inula racemose[J]. CHEMISTRYSELECT,2020,5(2).
APA	Chi, Xiaofeng,Zhang, Guoying,&Chen, Shilong.(2020).Subcritical Water Extraction of Sesquiterpene Lactones from Inula racemose.CHEMISTRYSELECT,5(2).
MLA	Chi, Xiaofeng,et al."Subcritical Water Extraction of Sesquiterpene Lactones from Inula racemose".CHEMISTRYSELECT 5.2(2020).