Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses

NWIPB OpenIR

	Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses
	Pan, Zheng; Xiong, Feng; Chen, Yi-Long; Wan, Guo-Guo; Zhang, Yi; Chen, Zhi-Wei; Cao, Wen-Fu; Zhou, Guo-Ying
	2019
发表期刊	MOLECULES
卷号	24 期号:24
摘要	The root of Gentiana straminea Maxim. (Gentianaceae), is officially listed as "Qin-Jiao" in the Chinese Pharmacopoeia for the treatment of rheumatic arthritis, icteric hepatitis, constipation, pain, and hypertension. To establish the geographical origin traceability in G. straminea, its chemical profiles were determined by a UPLC-Q exactive mass spectrometer, from which 43 compounds were identified by comparing retention times and mass spectrometry. Meanwhile, a pair of isomers (loganin and secologanol) was identified by mass spectrometry based on their fragmentation pathway. A total of 42 samples from difference habitats were determined by an UPLC-Q exactive mass spectrometer and the data were assayed with multivariate statistical analysis. Eight characteristic compounds were identified to determine the geographical origin of the herb. To estimate the key characteristic markers associated with pharmacological function, the inhibiting activities of nitric oxide (NO) production in lipopolysaccharide (LPS)-induced macrophages were examined. This finding is crucial in realizing the determination of botanical origin and evaluating the quality of G. straminea.
关键词	Gentiana straminea geographical origin UPLC-Q exactive mass metabolomics multivariate analysis
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/60483
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Pan, Zheng,Xiong, Feng,Chen, Yi-Long,et al. Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses[J]. MOLECULES,2019,24(24).
APA	Pan, Zheng.,Xiong, Feng.,Chen, Yi-Long.,Wan, Guo-Guo.,Zhang, Yi.,...&Zhou, Guo-Ying.(2019).Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses.MOLECULES,24(24).
MLA	Pan, Zheng,et al."Traceability of Geographical Origin in Gentiana straminea by UPLC-Q Exactive Mass and Multivariate Analyses".MOLECULES 24.24(2019).