NWIPB OpenIR
The Gut Microbiota Determines the High-Altitude Adaptability of Tibetan Wild Asses (Equus kiang) in Qinghai-Tibet Plateau
Liu, HJ; Han, XP; Zhao, N; Hu, LY; Wang, XG; Luo, CL; Chen, YW; Zhao, XQ; Xu, SX
2022
发表期刊FRONTIERS IN MICROBIOLOGY
卷号13
摘要It was acknowledged long ago that microorganisms have played critical roles in animal evolution. Tibetan wild asses (TWA, Equus kiang) are the only wild perissodactyls on the Qinghai-Tibet Plateau (QTP) and the first national protected animals; however, knowledge about the relationships between their gut microbiota and the host's adaptability remains poorly understood. Herein, 16S rRNA and meta-genomic sequencing approaches were employed to investigate the gut microbiota-host associations in TWA and were compared against those of the co-resident livestock of yak (Bos grunnies) and Tibetan sheep (Ovis aries). Results revealed that the gut microbiota of yak and Tibetan sheep underwent convergent evolution. By contrast, the intestinal microflora of TWA diverged in a direction enabling the host to subsist on sparse and low-quality forage. Meanwhile, high microbial diversity (Shannon and Chao1 indices), cellulolytic activity, and abundant indicator species such as Spirochaetes, Bacteroidetes, Prevotella_1, and Treponema_2 supported forage digestion and short-chain fatty acid production in the gut of TWA. Meanwhile, the enterotype identification analysis showed that TWA shifted their enterotype in response to low-quality forage for a better utilization of forage nitrogen and short-chain fatty acid production. Metagenomic analysis revealed that plant biomass degrading microbial consortia, genes, and enzymes like the cellulolytic strains (Prevotella ruminicola, Ruminococcus flavefaciens, Ruminococcus albus, Butyrivibrio fibrisolvens, and Ruminobacter amylophilus), as well as carbohydrate metabolism genes (GH43, GH3, GH31, GH5, and GH10) and enzymes (beta-glucosidase, xylanase, and beta-xylosidase, etc.) had a significantly higher enrichment in TWA. Our results indicate that gut microbiota can improve the adaptability of TWA through plant biomass degradation and energy maintenance by the functions of gut microbiota in the face of nutritional deficiencies and also provide a strong rationale for understanding the roles of gut microbiota in the adaptation of QTP wildlife when facing harsh feeding environments.
收录类别SCIE
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/61152
专题中国科学院西北高原生物研究所
推荐引用方式
GB/T 7714
Liu, HJ,Han, XP,Zhao, N,et al. The Gut Microbiota Determines the High-Altitude Adaptability of Tibetan Wild Asses (Equus kiang) in Qinghai-Tibet Plateau[J]. FRONTIERS IN MICROBIOLOGY,2022,13.
APA Liu, HJ.,Han, XP.,Zhao, N.,Hu, LY.,Wang, XG.,...&Xu, SX.(2022).The Gut Microbiota Determines the High-Altitude Adaptability of Tibetan Wild Asses (Equus kiang) in Qinghai-Tibet Plateau.FRONTIERS IN MICROBIOLOGY,13.
MLA Liu, HJ,et al."The Gut Microbiota Determines the High-Altitude Adaptability of Tibetan Wild Asses (Equus kiang) in Qinghai-Tibet Plateau".FRONTIERS IN MICROBIOLOGY 13(2022).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Liu, HJ]的文章
[Han, XP]的文章
[Zhao, N]的文章
百度学术
百度学术中相似的文章
[Liu, HJ]的文章
[Han, XP]的文章
[Zhao, N]的文章
必应学术
必应学术中相似的文章
[Liu, HJ]的文章
[Han, XP]的文章
[Zhao, N]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。