Metagenomics reveals the self-recovery and risk of antibiotic resistomes during carcass decomposition of wild mammals

NWIPB OpenIR

	Metagenomics reveals the self-recovery and risk of antibiotic resistomes during carcass decomposition of wild mammals
	Yu, Qiaoling; Han, Qian; Li, Tongtong; Kou, Yongping; Zhang, Xiao; Wang, Yansu; Li, Guoliang; Zhou, Huakun; Qu, Jiapeng; Li, Huan
	2023
发表期刊	ENVIRONMENTAL RESEARCH
卷号	238
摘要	Animal carcass decomposition may bring serious harm to the environment, including pathogenic viruses, toxic gases and metabolites, and antibiotic resistance genes (ARGs). However, how wild mammal corpses decompo-sition influence and change ARGs in the environment has less explored. Through metagenomics, 16S rRNA gene sequencing, and physicochemical analysis, this study explored the succession patterns, influencing factors, and assembly process of ARGs and mobile genetic elements (MGEs) in gravesoil during long-term corpse decom-position of wild mammals. Our results indicate that the ARG and MGE communities related to wildlife corpses exhibited a pattern of differentiation first and then convergence. Different from the farmed animals, the decomposition of wild animals first reduced the diversity of ARGs and MGEs, and then recovered to a level similar to that of the control group (untreated soil). ARGs and MGEs of the gravesoil are mainly affected by deterministic processes in different stages. MGEs and bacterial community are the two most important factors affecting ARGs in gravesoil. It is worth noting that the decomposition of wild animal carcasses enriched different high-risk ARGs at different stages (bacA, mecA and floR), which have co-occurrence patterns with opportunistic pathogens (Comamonas and Acinetobacter), thereby posing a great threat to public health. These results are of great significance for wildlife corpse management and environmental and ecological safety.
收录类别	SCIE
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/61548
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Yu, Qiaoling,Han, Qian,Li, Tongtong,et al. Metagenomics reveals the self-recovery and risk of antibiotic resistomes during carcass decomposition of wild mammals[J]. ENVIRONMENTAL RESEARCH,2023,238.
APA	Yu, Qiaoling.,Han, Qian.,Li, Tongtong.,Kou, Yongping.,Zhang, Xiao.,...&Li, Huan.(2023).Metagenomics reveals the self-recovery and risk of antibiotic resistomes during carcass decomposition of wild mammals.ENVIRONMENTAL RESEARCH,238.
MLA	Yu, Qiaoling,et al."Metagenomics reveals the self-recovery and risk of antibiotic resistomes during carcass decomposition of wild mammals".ENVIRONMENTAL RESEARCH 238(2023).