Knowledge Management System of Northwest Institute of Plateau Biology, CAS
Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones | |
Mao, Beibei1,2; Qu, Fei1,2; Zhu, Shuyun1,2,3; You, Jinmao1,2,3 | |
2016-10-29 | |
发表期刊 | SENSORS AND ACTUATORS B-CHEMICAL |
卷号 | 234页码:338-344 |
文章类型 | Article |
摘要 | Herein, utilizing fluorescent Ag nanoclusters (Ag NCs) capped by polyethyleneimine (PEI) with different molecular weights, we constructed a novel Ag NCs-Cu2+ sensing system based on fluorescence turn-on strategy for trace detection of quinolones, including nalidixic acid, cinoxacin, ciprofloxacin/ofloxacin, and moxifloxacin; these were the representatives of four generations of quinolone antibacterial drugs. The fluorescence of Ag NCs could be efficiently quenched by Cu2+, while with the addition of quinolones, the fluorescence of this system recovered rapidly. This protocol exhibited excellent sensitivities to these five quinolones. For instance, the linear ranges were from 1 to 100 nM for nalidixic acid with limit of detection (LOD) 0.47 nM, from 1 to 80 nM for cinoxacin with LOD 0.43 nM, from 0.1 to 120 nM for ciprofloxacin with LOD 38 pM, from 0.1 to 80 nM for ofloxacin with LOD 49 pM, and from 0.1 to 120 nM for moxifloxacin with LOD 48 pM, respectively, revealing that this approach showed low detection limits and wide linear ranges. Benefiting from the high sensitivity, the satisfactory recoveries were obtained for trace detection of quinolones in real samples, such as tablets, human urine and serum. (C) 2016 Elsevier B.V. All rights reserved. |
关键词 | Ag Nanoclusters Polyethyleneimine Quinolones Trace Detecion |
WOS标题词 | Science & Technology ; Physical Sciences ; Technology |
DOI | 10.1016/j.snb.2016.04.174 |
关键词[WOS] | PERFORMANCE LIQUID-CHROMATOGRAPHY ; TANDEM MASS-SPECTROMETRY ; CAPILLARY-ZONE-ELECTROPHORESIS ; ULTRAVIOLET DETECTION ; FLUOROQUINOLONES ; SAMPLES ; CIPROFLOXACIN ; ANTIBIOTICS ; MOXIFLOXACIN ; EXTRACTION |
收录类别 | SCI |
语种 | 英语 |
项目资助者 | National Natural Science Foundation of China(21405093 ; Scientific Research Foundation of Qufu Normal University(BSQD20130117) ; 201405094) |
WOS研究方向 | Chemistry ; Electrochemistry ; Instruments & Instrumentation |
WOS类目 | Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation |
WOS记录号 | WOS:000378538700042 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/6479 |
专题 | 中国科学院西北高原生物研究所 |
作者单位 | 1.Qufu Normal Univ, Key Lab Life Organ Anal, Qufu 273165, Shandong, Peoples R China 2.Qufu Normal Univ, Key Lab Pharmaceut Intermediates & Anal Nat Med, Qufu 273165, Shandong, Peoples R China 3.Chinese Acad Sci, Northwest Inst Plateau Biol, Xining 810001, Peoples R China |
推荐引用方式 GB/T 7714 | Mao, Beibei,Qu, Fei,Zhu, Shuyun,et al. Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones[J]. SENSORS AND ACTUATORS B-CHEMICAL,2016,234:338-344. |
APA | Mao, Beibei,Qu, Fei,Zhu, Shuyun,&You, Jinmao.(2016).Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones.SENSORS AND ACTUATORS B-CHEMICAL,234,338-344. |
MLA | Mao, Beibei,et al."Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones".SENSORS AND ACTUATORS B-CHEMICAL 234(2016):338-344. |
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