Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments

doi:10.1186/s12862-015-0581-0

NWIPB OpenIR

	Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments
	Xu, Qianghua 1,3; Zhang, Chi 1; Zhang, Dongsheng 2; Jiang, Huapeng 1; Peng, Sihua 2; Liu, Yang 1; Zhao, Kai 4; Wang, Congcong 1; Chen, Liangbiao 2
	2016-01-15
发表期刊	BMC EVOLUTIONARY BIOLOGY
卷号	16
文章类型	Article
摘要	Background: Erythropoietin (EPO) is a glycoprotein hormone that plays a principal regulatory role in erythropoiesis and initiates cell homeostatic responses to environmental challenges. The Qinghai-Tibet Plateau is a natural laboratory for hypoxia adaptation. Gymnocypris dobula is a highly specialized plateau schizothoracine fish that is restricted to >4500 m high-altitude freshwater rivers and ponds in the Qinghai-Tibet Plateau. The role of EPO in the adaptation of schizothoracine fish to hypoxia is unknown.
关键词	Epo Qinghai-tibet Plateau Schizothoracine Fish Hypoxia Adaptation Positive Selection
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1186/s12862-015-0581-0
关键词[WOS]	HIGH-ALTITUDE ADAPTATION ; ZOKOR MYOSPALAX-BAILEYI ; MITOCHONDRIAL GENOME ; OCHOTONA-CURZONIAE ; CDNA CLONING ; EXPRESSION ; PROTEINS ; CELLS ; MODEL ; GENE
收录类别	SCI
语种	英语
项目资助者	National Natural Science Foundation of China(31130049) ; Research Project of the Chinese Ministry of Education(213013A) ; Shanghai Education Development Foundation ; Shanghai Municipal Education Commission(13SG51) ; Major Research Plan Fostering Project of the National Natural Science Foundation of China(91131006) ; Shanghai Municipal Project for First-Class Discipline of Fishery to Shanghai Ocean University
WOS研究方向	Evolutionary Biology ; Genetics & Heredity
WOS类目	Evolutionary Biology ; Genetics & Heredity
WOS记录号	WOS:000368224500001
引用统计	被引频次：29[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/6503
专题	中国科学院西北高原生物研究所
作者单位	1.Shanghai Ocean Univ, Coll Marine Sci, Key Lab Sustainable Exploitat Ocean Fisheries Res, Minist Educ, Shanghai, Peoples R China 2.Shanghai Ocean Univ, Coll Fisheries & Life Sci, Key Lab Aquaculture Resources & Utilizat, Minist Educ, Shanghai, Peoples R China 3.Collaborat Innovat Ctr Distant Water Fisheries, Shanghai, Peoples R China 4.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining, Peoples R China
推荐引用方式 GB/T 7714	Xu, Qianghua,Zhang, Chi,Zhang, Dongsheng,et al. Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments[J]. BMC EVOLUTIONARY BIOLOGY,2016,16.
APA	Xu, Qianghua.,Zhang, Chi.,Zhang, Dongsheng.,Jiang, Huapeng.,Peng, Sihua.,...&Chen, Liangbiao.(2016).Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments.BMC EVOLUTIONARY BIOLOGY,16.
MLA	Xu, Qianghua,et al."Analysis of the erythropoietin of a Tibetan Plateau schizothoracine fish (Gymnocypris dobula) reveals enhanced cytoprotection function in hypoxic environments".BMC EVOLUTIONARY BIOLOGY 16(2016).