New monoterpenes from stalks and infructescence of Sibiraea leavigata

doi:10.1016/j.phytol.2016.08.016

NWIPB OpenIR

	New monoterpenes from stalks and infructescence of Sibiraea leavigata
	Zhao, Jian-Qiang 1,5; Wang, Yan-Ming 2,3,5; Lv, Jun-Jiang 4; Wang, Shuo 1; Mei, Li-Juan 1; Tao, Yan-Duo 1
	2016-12-01
发表期刊	PHYTOCHEMISTRY LETTERS
卷号	18 页码:1-4
文章类型	Article
摘要	Chemical investigation of the ethanol extract of the stalks and infructescence of Sibiraea leavigata led to the isolation of two new monoterpenes named (4R)-2-(2-hydroxy-4-methyl-3-pentenyl) furan-2(5H)one (1) and (2R, 4R)-2-(2-hydroxyethyl)-4-(2-methyl-1-propenyl) furan-5H-2-one (2) along with eight known phenylpropanoids (3-10). Their structures were established on the basis of the interpretation of spectroscopic data and electronic circular dichroism (ECD) calculations. In addition, all of these isolates were evaluated for their cytotoxic activity. The results showed that compound 3 displayed moderate cytotoxicity with IC50 values ranging from 10.8 to 49.2 mu g mL(-1) against five cell lines. While 1 showed selective promotion effects on proliferation of gastric cancer MGC803 and RSC96 cell lines. (C) 2016 Phytochemical Society of Europe. Published by Elsevier Ltd. All rights reserved.
关键词	Monoterpenes Sibiraea Leavigata Cytotoxic Activity
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1016/j.phytol.2016.08.016
关键词[WOS]	CONSTITUENTS ; ANGUSTATA
收录类别	SCI
语种	英语
项目资助者	Significant Science & Technological Project of Qinghai Province(2014-GX-A3A)
WOS研究方向	Plant Sciences ; Oncology
WOS类目	Plant Sciences ; Oncology
WOS记录号	WOS:000389521800001
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/6648
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China 2.Chinese Acad Sci, Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Peoples R China 3.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Peoples R China 4.Chongqing Univ, Chem & Chem Engn Coll, Chongqing 400030, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Jian-Qiang,Wang, Yan-Ming,Lv, Jun-Jiang,et al. New monoterpenes from stalks and infructescence of Sibiraea leavigata[J]. PHYTOCHEMISTRY LETTERS,2016,18:1-4.
APA	Zhao, Jian-Qiang,Wang, Yan-Ming,Lv, Jun-Jiang,Wang, Shuo,Mei, Li-Juan,&Tao, Yan-Duo.(2016).New monoterpenes from stalks and infructescence of Sibiraea leavigata.PHYTOCHEMISTRY LETTERS,18,1-4.
MLA	Zhao, Jian-Qiang,et al."New monoterpenes from stalks and infructescence of Sibiraea leavigata".PHYTOCHEMISTRY LETTERS 18(2016):1-4.