Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products

doi:10.1021/acs.jafc.6b04104

NWIPB OpenIR

	Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products
	Zhang, Shijuan 1,2; Yu, Qiuhui 1,2; Sheng, Cuncun 1,2; You, Jinmao 1,2,3
	2016-12-14
发表期刊	JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷号	64 期号:49 页码:9452-9458
文章类型	Article
摘要	A green, sensitive, and accurate method was developed for the extraction and determination of bromophenols (BPs) from aquatic products by using organic solvent-free gas purge microsyringe extraction (GP-MSE) technique in combination with stable isotope labeling (SIL) strategy. BPs were extracted by NaHCO3 buffer solution, with recoveries varying from 92.0% to 98.5%. The extracted solution was analyzed by SIL strategy, during which analytes and standards were labeled by 10-methyl-acridone-2-sulfonyl chloride (d(0)-MASC) and its deuterated counterpart d(3)-MASC, respectively. The labeling reaction was finished within 10 min with good stability. The liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) sensitivity of BPs was greatly enhanced due to the mass-enhancing property of MASC, while the matrix effect was effectively minimized by the SIL strategy. The limits of detection (LODs) were in the range of 0.10-0.30 mu g/kg, while the limits of quantitations (LOQs) were in the range of 0.32-1.0 mu g/kg. The proposed method also showed great potential in the qualitative analysis of other bromophenols in the absence of standard.
关键词	Bromophenols Gp-mse Stable Isotope Labeling Aquatic Products
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
DOI	10.1021/acs.jafc.6b04104
关键词[WOS]	TANDEM MASS-SPECTROMETRY ; POLYBROMINATED DIPHENYL ETHERS ; BROMINATED FLAME RETARDANTS ; DILUTION ANALYSIS ; IONIZATION ; SAMPLES ; WATER ; ENHANCEMENT ; EXTRACTION ; MS/MS
收录类别	SCI
语种	英语
项目资助者	National Science Foundation of China(21475075) ; Natural Science Foundation of Shandong Province(ZR2014BQ009) ; experimental research project of Qufu Normal University(SJ201504)
WOS研究方向	Agriculture ; Chemistry ; Food Science & Technology
WOS类目	Agriculture, Multidisciplinary ; Chemistry, Applied ; Food Science & Technology
WOS记录号	WOS:000389962900023
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/6658
专题	中国科学院西北高原生物研究所
作者单位	1.Qufu Normal Univ, Shandong Prov Key Lab Life Organ Anal, West Jingxuan Rd 57, Qufu 273165, Peoples R China 2.Qufu Normal Univ, Key Lab Pharmaceut Intermediates & Anal Nat Med, Qufu 273165, Peoples R China 3.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810008, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Shijuan,Yu, Qiuhui,Sheng, Cuncun,et al. Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2016,64(49):9452-9458.
APA	Zhang, Shijuan,Yu, Qiuhui,Sheng, Cuncun,&You, Jinmao.(2016).Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,64(49),9452-9458.
MLA	Zhang, Shijuan,et al."Gas Purge Microextraction Coupled with Stable Isotope Labeling-Liquid Chromatography/Mass Spectrometry for the Analysis of Bromophenols in Aquatic Products".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 64.49(2016):9452-9458.