Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus

doi:10.1080/14786419.2016.1247083

NWIPB OpenIR

	Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus
	Wang, Yan-Ming 1,2; Zhao, Jian-Qiang 3; Yang, Jun-Li 1,2; Tao, Yan-Duo 3; Mei, Li-Juan 3; Shi, Yan-Ping 1,2
	2017
发表期刊	NATURAL PRODUCT RESEARCH
卷号	31 期号:12 页码:1365-1369
文章类型	Article
摘要	A new flavonoid, along with 16 known ones, was separated from the aerial parts of Asterothamnus centrali-asiaticus. Their structures were elucidated by extensive spectroscopic methods, including 1D and 2D NMR techniques and HRESIMS. To confirm the structure of the new compound, computational prediction of its C-13 chemical shifts was performed. All of the 17 flavonoids were reported from A. centrali-asiaticus for the first time. In addition, all flavonoids were evaluated for their antioxidant and -glucosidase inhibitory activities. The results showed that 10 of them exhibited antioxidant activity. Meanwhile, four flavonoids displayed -glucosidase inhibitory effect with IC50 values ranging from 38.9 to 299.7 mu M.
关键词	Asterothamnus Centrali-asiaticus Flavonoids Antioxidants Alpha-glucosidase Inhibitors
WOS标题词	Science & Technology ; Physical Sciences ; Life Sciences & Biomedicine
DOI	10.1080/14786419.2016.1247083
关键词[WOS]	POLYPHENOLS
收录类别	SCI
语种	英语
项目资助者	National Nature Science Foundation of China(21375136 ; scientific research project of Central Asia Drug Discovery and Development Centre of Chinese Academy of Sciences(CAM201404) ; CAS Pioneer Hundred Talents Program ; 21575150)
WOS研究方向	Chemistry ; Pharmacology & Pharmacy
WOS类目	Chemistry, Applied ; Chemistry, Medicinal
WOS记录号	WOS:000395165600003
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/6830
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources CAS, Lanzhou, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou, Peoples R China 3.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yan-Ming,Zhao, Jian-Qiang,Yang, Jun-Li,et al. Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus[J]. NATURAL PRODUCT RESEARCH,2017,31(12):1365-1369.
APA	Wang, Yan-Ming,Zhao, Jian-Qiang,Yang, Jun-Li,Tao, Yan-Duo,Mei, Li-Juan,&Shi, Yan-Ping.(2017).Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus.NATURAL PRODUCT RESEARCH,31(12),1365-1369.
MLA	Wang, Yan-Ming,et al."Separation of antioxidant and -glucosidase inhibitory flavonoids from the aerial parts of Asterothamnus centrali-asiaticus".NATURAL PRODUCT RESEARCH 31.12(2017):1365-1369.