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A new oxygen-binding globin: Neuroglobin
Zhao, TB; Chang, ZJ; Zhao, XQ
2003-12-01
发表期刊PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
卷号30期号:6页码:844-846
文章类型Article
摘要Neuroglobin (NGB) is a newly discovered member of the hemoglobin family that reversibly binds O-2 and is expressed predominately in vertebrate brain. NGB is a monomer composed of 151 amino acids, with high oxygen affinity. It is of ancient evolutionary origin. Hithertos, it has been proved to associate with oxygen storage, transport and neuron protection. NGB gene expression is mediated by at least 2 signal transduction pathways. The discovery of NGB provides a new direction for treating patients with strokes and other hypoxia-related diseases.
关键词Neuroglobin (Ngb) Oxygen Brain Neuron
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]LIGAND-BINDING ; PROTECTS ; BRAIN
收录类别SCI
语种英语
WOS研究方向Biochemistry & Molecular Biology ; Biophysics
WOS类目Biochemistry & Molecular Biology ; Biophysics
WOS记录号WOS:000224108900004
引用统计
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/6943
专题中国科学院西北高原生物研究所
作者单位1.Chinese Acad Sci, NW Plateau Inst Biol, Xining 810001, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Tsing Hua Univ, Dept Biol Sci & Biotechnol, Tsinghua Inst Genome Res, Beijing 100084, Peoples R China
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Zhao, TB,Chang, ZJ,Zhao, XQ. A new oxygen-binding globin: Neuroglobin[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2003,30(6):844-846.
APA Zhao, TB,Chang, ZJ,&Zhao, XQ.(2003).A new oxygen-binding globin: Neuroglobin.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,30(6),844-846.
MLA Zhao, TB,et al."A new oxygen-binding globin: Neuroglobin".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 30.6(2003):844-846.
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