NWIPB OpenIR
Integrated mRNA and microRNA transcriptome analyses reveal regulation of thermal acclimation in Gymnocypris przewalskii: A case study in Tibetan Schizothoracine fish
Zhang, Cunfang1; Tong, Chao1,2; Tian, Fei1; Zhao, Kai1
2017-10-18
发表期刊PLOS ONE
ISSN1932-6203
卷号12期号:10
文章类型Article
摘要Environmental acclimation is important episode in wildlife occupation of the high-altitude Tibetan Plateau (TP). Transcriptome-wide studies on thermal acclimation mechanism in fish species are rarely revealed in Tibetan Plateau fish at high altitude. Thus, we used mRNA and miRNA transcriptome sequencing to investigate regulation of thermal acclimation in larval Tibetan naked carp, Gymnocypris przewalskii. We first remodeled the regulation network of mRNA and miRNA in thermal acclimation, and then identified differential expression of miRNAs and target mRNAs enriched in metabolic and digestive pathways. Interestingly, we identified two candidate genes contributed to normal skeletal development. The altered expression of these gene groups could potentially be associated with the developmental issues of deformity and induced larval death. Our results have three important implications: first, these findings provide strong evidences to support our hypothesis that G. przewalskii possess ability to build heat-tolerance against the controversial issue. Second, this study shows that transcriptional and post-transcriptional regulations are extensively involved in thermal acclimation. Third, the integrated mRNA and microRNA transcriptome analyses provide a large number of valuable genetic resources for future studies on environmental stress response in G. przewalskii and as a case study in Tibetan Schizothoracine fish.
WOS标题词Science & Technology
DOI10.1371/journal.pone.0186433
关键词[WOS]SALMON SALMO-SALAR ; HEAT-STRESS ; ENVIRONMENTAL-CHANGE ; CLIMATE-CHANGE ; TEMPERATURE ; EXPRESSION ; PHYSIOLOGY ; RESPONSES ; PLATEAU ; FAMILY
收录类别SCI
语种英语
项目资助者National Natural Science Foundation of China(31572258 ; West Light Foundation of Key Innovation Plan(KSCX2-EW-N-004) ; Natural Science Foundation of Qinghai Province, China(2016-ZJ-939Q) ; 31500306)
WOS研究方向Science & Technology - Other Topics
WOS类目Multidisciplinary Sciences
WOS记录号WOS:000413168100061
出版者PUBLIC LIBRARY SCIENCE
引用统计
被引频次:15[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://210.75.249.4/handle/363003/9831
专题中国科学院西北高原生物研究所
通讯作者Zhao, Kai
作者单位1.Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Anim Ecol Genom,Key Lab Adaptat &, Lab Plateau Fish Evolutionary & Funct Genom, Xining, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Cunfang,Tong, Chao,Tian, Fei,et al. Integrated mRNA and microRNA transcriptome analyses reveal regulation of thermal acclimation in Gymnocypris przewalskii: A case study in Tibetan Schizothoracine fish[J]. PLOS ONE,2017,12(10).
APA Zhang, Cunfang,Tong, Chao,Tian, Fei,&Zhao, Kai.(2017).Integrated mRNA and microRNA transcriptome analyses reveal regulation of thermal acclimation in Gymnocypris przewalskii: A case study in Tibetan Schizothoracine fish.PLOS ONE,12(10).
MLA Zhang, Cunfang,et al."Integrated mRNA and microRNA transcriptome analyses reveal regulation of thermal acclimation in Gymnocypris przewalskii: A case study in Tibetan Schizothoracine fish".PLOS ONE 12.10(2017).
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Zhang, Cunfang]的文章
[Tong, Chao]的文章
[Tian, Fei]的文章
百度学术
百度学术中相似的文章
[Zhang, Cunfang]的文章
[Tong, Chao]的文章
[Tian, Fei]的文章
必应学术
必应学术中相似的文章
[Zhang, Cunfang]的文章
[Tong, Chao]的文章
[Tian, Fei]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。