Knowledge Management System of Northwest Institute of Plateau Biology, CAS
Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch | |
Wei LX(魏立新); Peng M(彭敏) | |
2010-04-18 | |
发表期刊 | Journal of Medicinal Plants Research
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ISSN | 1996-0875 |
卷号 | 4期号:8页码:706-709 |
摘要 | Swertia mussotii Franch. (SM) (Gentianaceae) was a traditional Tibetan folk herb for hepatitis in the Qinghai-Tibet plateau areas. For understanding the hepatoprotection and toxicity characteristics of Swertia mussotii Franch., the whole plant of Swertia mussotii was extracted by water (SME-b) and 75% ethanol (SME-a); then, SME-a was dissolved with water, the supernatant was SME-c, and the sedimentation was SME-d. 17.76% SME-a, 14.48% SME-b, 10.13% SME-c, and 4.35%SME-d were extracted from Swertia mussotii. These four extracts were evaluated with acute toxicity and hepatoprotective effect on CCl4-induced acute liver damage in mice. The toxic material mainly reside in SME-c and SME-a. The hepatoprotective materials were in SME-a, SME-c and SME-d, while SME-b had no hepatoprotective activities. So, SME-a and SME-c had both the hepatoprotection and toxicity characteristics; SME-b had no toxicity or the hepatoprotection characteristics; only SME-d was hepatoprotective function without toxicity, which could be a good candidate for new drug healing the live disorder. |
收录类别 | SCI |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/2068 |
专题 | 中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Wei LX,Peng M. Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch[J]. Journal of Medicinal Plants Research,2010,4(8):706-709. |
APA | 魏立新,&彭敏.(2010).Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch.Journal of Medicinal Plants Research,4(8),706-709. |
MLA | 魏立新,et al."Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch".Journal of Medicinal Plants Research 4.8(2010):706-709. |
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