Sensitive determination of melamine leached from tableware by reversed phase high-performance liquid chromatography using 10-methyl-acridone-2-sulfonyl chloride as a pre-column fluorescent labeling reagent

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	Sensitive determination of melamine leached from tableware by reversed phase high-performance liquid chromatography using 10-methyl-acridone-2-sulfonyl chloride as a pre-column fluorescent labeling reagent
	Zhang, Shijuan 1,2,3; Yu, Zhaoqiang 4; Hu, Na 1,3; Sun, Yuanpeng 2; Suo, Yourui 1; You, Jinmao 1,2
	2014-05-01
发表期刊	FOOD CONTROL
ISSN	0956-7135
卷号	39 页码:25-29
文章类型	Article
摘要	A new and sensitive pre-column derivatization method was developed for the analysis of melamine leached from tableware by high performance liquid chromatography (HPLC) with fluorescence detection. The HPLC sensitivity was greatly enhanced by introducing 10-methyl-acridone-2-sulfonyl chloride (MASC) with excellent fluorescence property into the melamine molecule. Meanwhile, derivatization also greatly increased the hydrophobicity of melamine. Therefore, the common reversed phase column can be used for the HPLC analysis of highly hydrophilic melamine. The detection limit obtained by the proposed method was lower than 0.40 mu g/L. This is the first time that HPLC with fluorescence detection was applied to the analysis of melamine. The proposed method was successfully applied to the analysis of melamine leached from tableware. The results indicated that the leaching of melamine from tableware was obvious when hot water or milk was added. (C) 2013 Elsevier Ltd. All rights reserved.; A new and sensitive pre-column derivatization method was developed for the analysis of melamine leached from tableware by high performance liquid chromatography (HPLC) with fluorescence detection. The HPLC sensitivity was greatly enhanced by introducing 10-methyl-acridone-2-sulfonyl chloride (MASC) with excellent fluorescence property into the melamine molecule. Meanwhile, derivatization also greatly increased the hydrophobicity of melamine. Therefore, the common reversed phase column can be used for the HPLC analysis of highly hydrophilic melamine. The detection limit obtained by the proposed method was lower than 0.40 mu g/L. This is the first time that HPLC with fluorescence detection was applied to the analysis of melamine. The proposed method was successfully applied to the analysis of melamine leached from tableware. The results indicated that the leaching of melamine from tableware was obvious when hot water or milk was added. (C) 2013 Elsevier Ltd. All rights reserved.
关键词	Melamine Hplc Fluorescence Tableware
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	TANDEM MASS-SPECTROMETRY ; CYANURIC ACID ; DAIRY-PRODUCTS ; EXTRACTION ; MIGRATION ; COLUMN ; MILK ; FOOD
收录类别	SCI
语种	英语
WOS研究方向	Food Science & Technology
WOS类目	Food Science & Technology
WOS记录号	WOS:000331417400004
引用统计	被引频次：21[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/4238
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Tibetan Med Res, Xining 810001, Peoples R China 2.Qufu Normal Univ, Shandong Prov Key Lab Life Organ Anal, Qufu, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Lianyungang Water Supply Co Ltd, Lianyungang, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Shijuan,Yu, Zhaoqiang,Hu, Na,et al. Sensitive determination of melamine leached from tableware by reversed phase high-performance liquid chromatography using 10-methyl-acridone-2-sulfonyl chloride as a pre-column fluorescent labeling reagent[J]. FOOD CONTROL,2014,39:25-29.
APA	Zhang, Shijuan,Yu, Zhaoqiang,Hu, Na,Sun, Yuanpeng,Suo, Yourui,&You, Jinmao.(2014).Sensitive determination of melamine leached from tableware by reversed phase high-performance liquid chromatography using 10-methyl-acridone-2-sulfonyl chloride as a pre-column fluorescent labeling reagent.FOOD CONTROL,39,25-29.
MLA	Zhang, Shijuan,et al."Sensitive determination of melamine leached from tableware by reversed phase high-performance liquid chromatography using 10-methyl-acridone-2-sulfonyl chloride as a pre-column fluorescent labeling reagent".FOOD CONTROL 39(2014):25-29.