Two new sesquiterpenes from Artemisia sieversiana

NWIPB OpenIR

	Two new sesquiterpenes from Artemisia sieversiana
	Liu, Shi-Jun ; Liao, Zhi-Xin ; Liu, Chao ; Ji, Lan-Ju ; Sun, Hong-Fa
	2014-09-01
发表期刊	FITOTERAPIA ; Liu, SJ; Liao, ZX; Liu, C; Ji, LJ; Sun, HF.Two new sesquiterpenes from Artemisia sieversiana,FITOTERAPIA,2014,97():43
摘要	Two new sesquiterpenes, together with 32 known compounds(3-34), were isolated from Artemisia sieversiana Ehrhart ex willd. and the compounds 3-21 were isolated from this plant for the first time. The new compounds were elucidated as 2a,9a-dihydroxymuurol-3(4)-en-12-oic acid (1) and 13 alpha-methyl-(5 alpha H,6 alpha H,7 alpha H,8 alpha H)-austricin 8-O-beta-D-glucopyranoside (2), respectively. The structural identification of these compounds was mainly achieved by spectroscopic methods including 1D and 2D NMR techniques, and the structure of compound 1 was confirmed by a single crystal X-ray diffraction experiment. Compounds 1-2 were evaluated for cytotoxic activity in vitro against MCF-7, NCI-H460 and Hep-G2 cell lines, respectively. (c) 2014 Elsevier B.V. All rights reserved.; Two new sesquiterpenes, together with 32 known compounds(3-34), were isolated from Artemisia sieversiana Ehrhart ex willd. and the compounds 3-21 were isolated from this plant for the first time. The new compounds were elucidated as 2a,9a-dihydroxymuurol-3(4)-en-12-oic acid (1) and 13 alpha-methyl-(5 alpha H,6 alpha H,7 alpha H,8 alpha H)-austricin 8-O-beta-D-glucopyranoside (2), respectively. The structural identification of these compounds was mainly achieved by spectroscopic methods including 1D and 2D NMR techniques, and the structure of compound 1 was confirmed by a single crystal X-ray diffraction experiment. Compounds 1-2 were evaluated for cytotoxic activity in vitro against MCF-7, NCI-H460 and Hep-G2 cell lines, respectively. (c) 2014 Elsevier B.V. All rights reserved.
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/47522
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Liu, Shi-Jun,Liao, Zhi-Xin,Liu, Chao,et al. Two new sesquiterpenes from Artemisia sieversiana[J]. FITOTERAPIA, Liu, SJ; Liao, ZX; Liu, C; Ji, LJ; Sun, HF.Two new sesquiterpenes from Artemisia sieversiana,FITOTERAPIA,2014,97():43,2014.
APA	Liu, Shi-Jun,Liao, Zhi-Xin,Liu, Chao,Ji, Lan-Ju,&Sun, Hong-Fa.(2014).Two new sesquiterpenes from Artemisia sieversiana.FITOTERAPIA.
MLA	Liu, Shi-Jun,et al."Two new sesquiterpenes from Artemisia sieversiana".FITOTERAPIA (2014).